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There are 19 four-letter words containing H and 2O

BOHOboho n. (Informal) A bohemian.
boho n. A style of female fashion drawing on various bohemian and hippie influences, popular in the mid-2000s.
boho adj. (Informal) Bohemian.
BOOHbooh v. Archaic form of boo.
booh n. Archaic form of boo.
BOOH v. to show disapproval by making this sound, also BOO.
COHOcoho n. An anadromus and semelparous salmon, Oncorhynchus kisutch, found in the coastal regions of the northern…
COHO n. a Pacific salmon, also COHOE.
HOBOhobo n. (North America) A wandering homeless person, especially (historical) one illegally travelling by rail…
hobo n. (North America) Any migratory laborer, whether homeless or not.
hobo n. A kind of large handbag.
HOLOholo n. (Science fiction) hologram.
holo adj. (Biochemistry, of a protein) Bound by ligands.
holo- pref. Whole.
HOMOhomo n. (Colloquial, often derogatory) Clipping of homosexual.
homo n. (Uncountable, dated, US, Canada) Homogenized milk with a high butterfat content.
homo adj. (Colloquial, sometimes derogatory) Of or pertaining to homosexuality.
HOODhood n. A covering for the head attached to a larger garment such as a jacket or cloak.
hood n. A distinctively coloured fold of material, representing a university degree.
hood n. An enclosure that protects something, especially from above.
HOOFhoof n. The tip of a toe of an ungulate such as a horse, ox or deer, strengthened by a thick keratin covering.
hoof n. (Slang) The human foot.
hoof n. (Geometry, dated) An ungula.
HOOKhook n. A rod bent into a curved shape, typically with one end free and the other end secured to a rope or other attachment.
hook n. A barbed metal hook used for fishing; a fishhook.
hook n. Any of various hook-shaped agricultural implements such as a billhook.
HOONhoon n. (Australia, New Zealand, slang, derogatory) A worthless person; a hooligan or lout.
hoon n. (Australia, slang, dated) A pimp.
hoon n. (Australia, New Zealand, slang) A person who drives excessively quickly, loudly or irresponsibly; a…
HOOPhoop n. A circular band of metal used to bind a barrel.
hoop n. A ring; a circular band; anything resembling a hoop.
hoop n. A circular band of metal, wood, or similar material used for forming part of a framework such as an awning or tent.
HOORHOOR n. a Scots and Irish form of WHORE; a difficult or unpleasant thing.
HOOThoot n. A derisive cry or shout.
hoot n. The cry of an owl.
hoot n. (Slang) A fun event or person. (See hootenanny)
MOHOmoho n. The North Island takahē, an extinct rail of New Zealand.
moho n. Synonym of oo.
Moho prop.n. (Geology) Short for Mohorovičić discontinuity.
OOHSoohs v. Third-person singular simple present indicative form of ooh.
OOH v. to express surprise.
POOHpooh interj. Expressing dismissal, contempt, impatience, etc.
pooh interj. Expressing disgust at an unpleasant smell.
pooh interj. (Euphemistic) Alternative form of poo: a minced oath for ’shit’.
SHOOshoo v. (Transitive, informal) To induce someone or something to leave.
shoo v. (Intransitive, informal) To leave under inducement.
shoo v. (Informal, rare) To usher someone.
SOHOsoho interj. (Obsolete) ho; halloo; a word used in calling from a distant place.
Soho prop.n. An area of the West End, in central London.
Soho prop.n. An area partly in Sandwell borough, and partly in Birmingham, West Midlands, England, believed to be…
TOHOtoho interj. (Obsolete) tallyho (used to urge on a fox hunt).
TOHO n. a call to pointers or setters to stop.

Scrabble words — in black are valid world wide — in RED are not valid in North America — in GREEN are valid only in North America.
Definitions are short excerpt from the WikWik.org and 1Word.ws.

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