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There are 4 ten-letter words containing G, 3I, N and 2R

IRRELIGIONirreligion n. The state of being irreligious; irreligious sentiment or thought.
IRRELIGION n. the state of being irreligious.
IRRIGATINGirrigating v. Present participle of irrigate.
IRRIGATE v. to water by canals or watercourses.
IRRIGATIONirrigation n. The act or process of irrigating, or the state of being irrigated; especially, the operation of causing…
IRRIGATION n. the therapeutic flushing of a body part with a stream of liquid.
IRRITATINGirritating adj. Causing irritation, annoyance or pain.
irritating adj. Stimulating or exciting a response.
irritating v. Present participle of irritate.

Scrabble words — in black are valid world wide — in RED are not valid in North America — in GREEN are valid only in North America.
Definitions are short excerpt from the WikWik.org and 1Word.ws.

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