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There are 19 words containing F, P, R, 2S and 2U

PURPOSEFULNESSpurposefulness n. The state of being purposeful.
PURPOSEFUL n. showing purpose.
PURSEFULSpursefuls n. Plural of purseful.
PURSEFUL n. enough to fill a purse.
SPINULIFEROUSSPINULIFEROUS adj. bearing spinules.
SUBPREFECTURESsubprefectures n. Plural of subprefecture.
sub-prefectures n. Plural of sub-prefecture.
SUBPREFECTURE n. the office of subprefect.
SUPERFLUIDITIESsuperfluidities n. Plural of superfluidity.
SUPERFLUIDITY n. the state of being superfluid.
SUPERFLUIDSsuperfluids n. Plural of superfluid.
SUPERFLUID n. a superfluid substance.
SUPERFLUITIESsuperfluities n. Plural of superfluity.
SUPERFLUITY n. excess.
SUPERFLUOUSsuperfluous adj. In excess of what is required or sufficient.
SUPERFLUOUS adj. extraneous.
SUPERFLUOUSLYsuperfluously adv. In a superfluous manner.
SUPERFLUOUS adv. extraneous.
SUPERFLUOUSNESSsuperfluousness n. The state or quality of being superfluous.
SUPERFLUOUSNESS n. the state of being superfluous.
SUPERFLUXESsuperfluxes n. Plural of superflux.
SUPERFLUX n. (Shakespeare) superfluity.
SUPERFUNDSsuperfunds n. Plural of superfund.
superfunds v. Third-person singular simple present indicative form of superfund.
Superfunds n. Plural of Superfund.
SUPERFUSEsuperfuse v. (Obsolete, transitive) To pour (something) over or on something else.
SUPERFUSE v. to pour over.
SUPERFUSEDsuperfused v. Simple past tense and past participle of superfuse.
superfused adj. (Medicine) Subjected to superfusion.
SUPERFUSE v. to pour over.
SUPERFUSESsuperfuses v. Third-person singular simple present indicative form of superfuse.
SUPERFUSE v. to pour over.
SUPERFUSINGsuperfusing v. Present participle of superfuse.
SUPERFUSE v. to pour over.
SUPERFUSIONsuperfusion n. (Medicine) The continuous flowing of a sustaining fluid over the outside of an isolated organ.
SUPERFUSION n. the act of superfusing.
SUPERFUSIONSsuperfusions n. Plural of superfusion.
SUPERFUSION n. the act of superfusing.
UNSUPERFLUOUSunsuperfluous adj. Not superfluous.
UNSUPERFLUOUS adj. (Milton) not superfluous.

Scrabble words — in black are valid world wide — in RED are not valid in North America — in GREEN are valid only in North America.
Definitions are short excerpt from the WikWik.org and 1Word.ws.

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