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There are 12 words containing 2F, I, O, S and 2U

FRUCTIFEROUSfructiferous adj. Bearing fruit.
FRUCTIFEROUS adj. bearing fruit.
FRUCTIFEROUSLYFRUCTIFEROUS adv. bearing fruit.
FRUGIFEROUSfrugiferous adj. Bearing fruit.
FRUGIFEROUS adj. bearing fruit.
FURCIFEROUSfurciferous adj. (Archaic) rascally; scandalous.
FURCIFEROUS adj. bearing a forked appendage; rascally.
IMMUNODIFFUSIONimmunodiffusion n. A technique used to detect the reaction between an antigen and an antibody by observing the behavior…
IMMUNODIFFUSION n. any of various analytical techniques that involve antigen and antibody solutions diffusing toward each other in a gel until antibody binds specifically to antigen to form a precipitate.
SUFFRUTICOSEsuffruticose adj. (Botany) Having a woody base, but shrubby higher up.
SUFFRUTICOSE adj. of a perennial plant, having a woody base, but remaining herbaceous in upper part.
SUFFUMIGATIONsuffumigation n. The burning of substances to produce fumes as part of some magical rituals.
SUFFUMIGATION n. fumigation from below.
SUFFUMIGATIONSsuffumigations n. Plural of suffumigation.
SUFFUMIGATION n. fumigation from below.
SUFFUSIONsuffusion n. (Countable) The act of pouring a liquid over or soaking something.
suffusion n. (Countable) coat, coating, film, plating.
suffusion n. (Uncountable) The state of being wet.
SUFFUSIONSsuffusions n. Plural of suffusion.
SUFFUSION n. the act of suffusing.
UNFOSSILIFEROUSunfossiliferous adj. Not fossiliferous, nonfossiliferous.
UNFOSSILIFEROUS adj. not fossiliferous.
UNOFFICIOUSunofficious adj. Not officious.
UNOFFICIOUS adj. not officious.

Scrabble words — in black are valid world wide — in RED are not valid in North America — in GREEN are valid only in North America.
Definitions are short excerpt from the WikWik.org and 1Word.ws.

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