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There are 12 words containing 2F, 2I, 2O and U

FORAMINIFEROUSforaminiferous adj. Having small openings, or foramina.
foraminiferous adj. Pertaining to, or composed of, Foraminifera.
FORAMINIFEROUS adj. bearing foramina.
FOSSILIFEROUSfossiliferous adj. Containing fossils.
FOSSILIFEROUS adj. bearing fossils.
IMMUNODIFFUSIONimmunodiffusion n. A technique used to detect the reaction between an antigen and an antibody by observing the behavior…
IMMUNODIFFUSION n. any of various analytical techniques that involve antigen and antibody solutions diffusing toward each other in a gel until antibody binds specifically to antigen to form a precipitate.
INOFFICIOUSinofficious adj. (Obsolete) Indifferent to obligation or duty.
inofficious adj. (Obsolete) Not officious; not civil or attentive.
inofficious adj. (Obsolete, law) Contrary to one’s natural obligation or duty, as of a testament by which a child is…
INOFFICIOUSLYinofficiously adv. In an inofficious manner; without officiousness.
INOFFICIOUS adv. not officious.
INOFFICIOUSNESSinofficiousness n. The quality of being inofficious.
INOFFICIOUS n. not officious.
OFFICIOUSofficious adj. (Obsolete) Obliging, attentive, eager to please.
officious adj. Offensively intrusive or interfering in offering advice and services.
OFFICIOUS adj. volunteering one's services too eagerly.
OFFICIOUSLYofficiously adv. In an officious manner.
OFFICIOUS adv. volunteering one's services too eagerly.
OFFICIOUSNESSofficiousness n. The quality of being officious.
OFFICIOUS n. volunteering one's services too eagerly.
OFFICIOUSNESSESofficiousnesses n. Plural of officiousness.
OFFICIOUSNESS n. OFFICIOUS, volunteering one's services too eagerly.
UNFOSSILIFEROUSunfossiliferous adj. Not fossiliferous, nonfossiliferous.
UNFOSSILIFEROUS adj. not fossiliferous.
UNOFFICIOUSunofficious adj. Not officious.
UNOFFICIOUS adj. not officious.

Scrabble words — in black are valid world wide — in RED are not valid in North America — in GREEN are valid only in North America.
Definitions are short excerpt from the WikWik.org and 1Word.ws.

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