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There are 13 ten-letter words containing F, 2I, O, 2S and T

DISCOMFITSdiscomfits v. Third-person singular simple present indicative form of discomfit.
DISCOMFIT v. to disconcert or balk.
DISPROFITSdisprofits v. Third-person singular simple present indicative form of disprofit.
DISPROFIT v. (archaic) to cause to fail to profit.
FASHIONISTfashionist n. (Archaic) An obsequious follower of fashion.
FASHIONIST n. a follower or setter of fashion, also FASHIONISTA.
FASTIDIOUSfastidious adj. Excessively particular, demanding, or fussy about details, especially about tidiness and cleanliness.
fastidious adj. Overly concerned about tidiness and cleanliness.
fastidious adj. Difficult to please; quick to find fault.
FIBROSITISfibrositis n. Fibromyalgia.
FIBROSITIS n. inflammation of the nerve fibres.
FLORISTICSfloristics n. (Botany) The scientific study of the distribution of plants, especially on the regional level.
FLORISTICS n. the study of the numerical distributions of plants.
FORTISSIMIfortissimi n. Plural of fortissimo.
FORTISSIMO n. a very loud passage in music.
FORTISSIMOfortissimo adv. (Music) Indicating that the piece is played very loud.
fortissimo n. (Music) The dynamic sign indicating that the piece should be played fortissimo. Abbreviation: ff.
FORTISSIMO adj. (Italian) very loud; with the utmost strength or loudness.
FUMOSITIESfumosities n. Plural of fumosity.
FUMOSITY n. a fuming condition.
FUSIONISTSfusionists n. Plural of fusionist.
FUSIONIST n. an advocate of fusionism, a policy that favours unionism or coalition.
MOISTIFIESmoistifies v. Third-person singular simple present indicative form of moistify.
MOISTIFY v. to make moist.
PROFILISTSprofilists n. Plural of profilist.
PROFILIST n. one who draws profiles, also PROFILER.
SAINTFOINSsaintfoins n. Plural of saintfoin.
SAINTFOIN n. (French) a leguminous plant, used as fodder, also SAINFOIN.

Scrabble words — in black are valid world wide — in RED are not valid in North America — in GREEN are valid only in North America.
Definitions are short excerpt from the WikWik.org and 1Word.ws.

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