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There are 12 ten-letter words containing F, 2I, O, R and 2S

DISINFORMSdisinforms v. Third-person singular simple present indicative form of disinform.
DISINFORM v. to inform incorrectly, also MISINFORM.
DISPROFITSdisprofits v. Third-person singular simple present indicative form of disprofit.
DISPROFIT v. (archaic) to cause to fail to profit.
FIBROSITISfibrositis n. Fibromyalgia.
FIBROSITIS n. inflammation of the nerve fibres.
FLORISTICSfloristics n. (Botany) The scientific study of the distribution of plants, especially on the regional level.
FLORISTICS n. the study of the numerical distributions of plants.
FORTISSIMIfortissimi n. Plural of fortissimo.
FORTISSIMO n. a very loud passage in music.
FORTISSIMOfortissimo adv. (Music) Indicating that the piece is played very loud.
fortissimo n. (Music) The dynamic sign indicating that the piece should be played fortissimo. Abbreviation: ff.
FORTISSIMO adj. (Italian) very loud; with the utmost strength or loudness.
INFUSORIESinfusories n. Plural of infusory.
INFUSORY n. an infusorian.
MISINFORMSmisinforms v. Third-person singular simple present indicative form of misinform.
MISINFORM v. to inform incorrectly, also DISINFORM.
PROFILISTSprofilists n. Plural of profilist.
PROFILIST n. one who draws profiles, also PROFILER.
SCORIFIERSscorifiers n. Plural of scorifier.
SCORIFIER n. a thing which scorifies something; specifically a fireclay vessel used in the process of refining or assaying.
SOPORIFICSsoporifics n. Plural of soporific.
SOPORIFIC n. a drug producing sleep.
SUDORIFICSsudorifics n. Plural of sudorific.
SUDORIFIC n. a drug causing or inducing sweat.

Scrabble words — in black are valid world wide — in RED are not valid in North America — in GREEN are valid only in North America.
Definitions are short excerpt from the WikWik.org and 1Word.ws.

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