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There are 20 twelve-letter words containing F, 2O, P and 2S

FLUOROSCOPESfluoroscopes n. Plural of fluoroscope.
FLUOROSCOPE v. to examine by fluoroscope.
FOETOSCOPIESfoetoscopies n. Plural of foetoscopy.
FOETOSCOPY n. a procedure for viewing the fetus directly, within the uterus, also FETOSCOPY.
FORETOPMASTSforetopmasts n. Plural of foretopmast.
FORETOPMAST n. the mast above the foretop platform.
GREASEPROOFSgreaseproofs v. Third-person singular simple present indicative form of greaseproof.
GREASEPROOF n. paper proof against grease.
PHOTOFISSIONphotofission n. (Nuclear physics) Nuclear fission as the result of the absorption of a gamma ray or other high-energy photon.
photofission v. (Nuclear physics) To undergo, or cause to undergo, photofission.
PHOTOFISSION n. nuclear fission induced by gamma rays.
PHOTOFLASHESphotoflashes n. Plural of photoflash.
PHOTOFLASH n. a photographic flash.
POSTMODIFIESpostmodifies v. Third-person singular simple present indicative form of postmodify.
POSTMODIFY v. to modify the sense of (a word or phrase) by being placed after it.
PROFESSIONALprofessional n. A person who belongs to a profession.
professional n. A person who earns their living from a specified activity.
professional n. (Euphemistic) A prostitute.
PROFESSORATEprofessorate n. Professorship.
PROFESSORATE n. the office of a professor.
PROFESSORESSprofessoress n. (Archaic) A female professor.
PROFESSORESS n. a female professor.
PROFESSORIALprofessorial adj. Of, relating to, or characteristic of a professor or professors, or of a professorship or professorships.
PROFESSORIAL adj. of or like a professor.
PROFESSORIATprofessoriat n. Professors in general.
PROFESSORIAT n. the body of college and university teachers at an institution or in society, also PROFESSORIATE.
PROFOUNDNESSprofoundness n. The quality of being profound; profundity.
PROFOUNDNESS n. the state of being profound.
PUSSYFOOTERSpussyfooters n. Plural of pussyfooter.
PUSSYFOOTER n. one who pussyfoots.
PUSSYFOOTINGpussyfooting v. Present participle of pussyfoot.
PUSSYFOOTING n. the act of approaching a topic with great caution.
SHOWERPROOFSshowerproofs v. Third-person singular simple present indicative form of showerproof.
SHOWERPROOF v. to make clothes resistant to light rain.
SOPORIFEROUSsoporiferous adj. (Archaic) soporific, sleep-inducing.
SOPORIFEROUS adj. causing or tending to cause sleep.
TEASPOONFULSteaspoonfuls n. Plural of teaspoonful.
TEASPOONFUL n. the contents of a teaspoon.
TEASPOONSFULteaspoonsful n. Plural of teaspoonful.
TEASPOONFUL n. the contents of a teaspoon.
TOPLOFTINESStoploftiness n. The quality of being toplofty.
TOPLOFTINESS n. the state of being toplofty, high and mighty.

Scrabble words — in black are valid world wide — in RED are not valid in North America — in GREEN are valid only in North America.
Definitions are short excerpt from the WikWik.org and 1Word.ws.

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