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There are 12 ten-letter words containing F, 3I and 2S

FIBROSITISfibrositis n. Fibromyalgia.
FIBROSITIS n. inflammation of the nerve fibres.
FILARIASISfilariasis n. Any disease common in tropical and subtropical countries resulting from infestation of the lymphatic…
FILARIASIS n. a disease caused by the presence of filaria in the blood.
FINISHINGSfinishings n. Plural of finishing.
FINISHING n. the act of making an end.
FISSIONINGfissioning n. The act of splitting into two separate parts.
fissioning v. Present participle of fission.
FISSION v. to split into parts.
FORTISSIMIfortissimi n. Plural of fortissimo.
FORTISSIMO n. a very loud passage in music.
MOISTIFIESmoistifies v. Third-person singular simple present indicative form of moistify.
MOISTIFY v. to make moist.
RESINIFIESresinifies v. Third-person singular simple present indicative form of resinify.
RESINIFY v. to convert into resin.
SIGNIFIEDSsignifieds n. Plural of signified.
SIGNIFIED n. that which is meant.
SIGNIFIERSsignifiers n. Plural of signifier.
SIGNIFIER n. something that signifies.
SILICIFIESsilicifies v. Third-person singular simple present indicative form of silicify.
SILICIFY v. to convert into silica.
SIMPLIFIESsimplifies v. Third-person singular simple present indicative form of simplify.
SIMPLIFY v. to make simple.
SOLIDIFIESsolidifies v. Third-person singular simple present indicative form of solidify.
SOLIDIFY v. to make solid.

Scrabble words — in black are valid world wide — in RED are not valid in North America — in GREEN are valid only in North America.
Definitions are short excerpt from the WikWik.org and 1Word.ws.

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