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There are 6 words containing 2F, I, S and Z

EFFEMINIZESeffeminizes v. Third-person singular simple present indicative form of effeminize.
EFFEMINIZE v. (archaic) to make effeminate.
SCHIZOAFFECTIVEschizoaffective adj. (Psychiatry) Combining the symptoms of schizophrenia with those of bipolar disorder.
schizoaffective n. A person who has a schizoaffective disorder.
ZAFFIRSZAFFIR n. (Italian) an impure oxide of cobalt, also ZAFFAR, ZAFFER, ZAFFRE.
ZIFFIUSziffius n. Obsolete form of xiphias.
ZIFFIUS n. (Spenser) a sea-monster, perhaps a swordfish.
ZIFFIUSESZIFFIUS n. (Spenser) a sea-monster, perhaps a swordfish.
ZIFFSziffs n. Plural of ziff.
Ziffs prop.n. Plural of Ziff.
ZIFF n. (Australian slang) a beard, a goatee.

Scrabble words — in black are valid world wide — in RED are not valid in North America — in GREEN are valid only in North America.
Definitions are short excerpt from the WikWik.org and 1Word.ws.

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