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There are 4 five-letter words containing F, M, R and U

FEMURfemur n. (Anatomy) A thighbone.
femur n. (Entomology) The middle segment of the leg of an insect, between the trochanter and the tibia.
femur n. (Arachnology) A segment of the leg of an arachnid.
FORUMforum n. A place for discussion.
forum n. A gathering for the purpose of discussion.
forum n. A form of discussion involving a panel of presenters and often participation by members of the audience.
FRUMPfrump n. (Countable, colloquial) A frumpy person, somebody who is unattractive, drab or dowdy.
frump n. (Uncountable, colloquial) Unattractive, dowdy clothes.
frump n. (Countable, dated) A bad-tempered person.
FUMERfumer n. One who makes or uses perfumes.
fumer n. That which fumes, something that produces or emits smoke or other vapor.
FUMER n. one that fumes.

Scrabble words — in black are valid world wide — in RED are not valid in North America — in GREEN are valid only in North America.
Definitions are short excerpt from the WikWik.org and 1Word.ws.

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