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There are 15 twelve-letter words containing F, H, P and U

DRAUGHTPROOFdraughtproof adj. That prevents the entry of draughts.
draughtproof v. To seal an opening, so as to prevent the entry of draughts.
DRAUGHTPROOF v. to make proof against draughts.
FLUOROGRAPHYfluorography n. Photofluorography.
fluorography n. Visualisation of radiolabelled material.
FLUOROGRAPHY n. the photography of the image produced on a fluorescent screen by X rays.
FLUOROPHORESfluorophores n. Plural of fluorophore.
FLUOROPHORE n. a chemical group responsible for fluorescence.
FLUPHENAZINEfluphenazine n. (Pharmacology) An antipsychotic drug of the phenothiazine class, which can be administered orally or by injection.
FLUPHENAZINE n. a tranquilizer used esp. in the form of its hydrochloride.
FRUMPISHNESSfrumpishness n. The quality of being frumpish.
FRUMPISHNESS n. the state of being frumpish.
HERPETOFAUNAherpetofauna n. Reptiles and amphibians as a group, especially those of a particular region or time period.
HERPETOFAUNA n. (Latin) snake life.
HYPERSURFACEhypersurface n. (Mathematics) A n-dimensional surface in a space (often a Euclidean space) of dimension n+1.
HYPERSURFACE n. a figure that is the analogue in hyperspace of a surface in three-dimensional space.
PLOUGHSTAFFSploughstaffs n. Plural of ploughstaff.
PLOUGHSTAFF n. one of the handles of a plough, also PLOWSTAFF.
PUFFERFISHESpufferfishes n. Plural of pufferfish.
PUFFERFISH n. a kind of fish, capable of inflating its body.
SPRACHGEFUHLsprachgefuhl n. Alternative form of Sprachgefühl.
sprachgefühl n. Alternative form of Sprachgefühl.
Sprachgefühl n. The instinctive or intuitive grasp of the natural idiom of a language.
SPRIGHTFULLYsprightfully adv. In a sprightful manner.
SPRIGHTFUL adv. (obsolete) full of spirit or of life.
SULFORAPHANEsulforaphane n. (Organic chemistry, medicine) An antimicrobial compound, 1-isothiocyanato-4-methylsulfinylbutane, that…
UNFRIENDSHIPunfriendship n. Unfriendliness; enmity.
UNFRIENDSHIP n. (archaic) unfriendliness.
UNWORSHIPFULunworshipful adj. Not worshipful.
UNWORSHIPFUL adj. not worshipful.
WORSHIPFULLYworshipfully adv. In a worshipful manner; reverentially.
WORSHIPFUL adv. entitled to worship.

Scrabble words — in black are valid world wide — in RED are not valid in North America — in GREEN are valid only in North America.
Definitions are short excerpt from the WikWik.org and 1Word.ws.

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