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There are 18 twelve-letter words containing E, O, R, S, 3T and U

AUTODESTRUCTautodestruct v. (Intransitive, chiefly science fiction) To destroy itself by design (as of a mechanical system).
autodestruct n. (Chiefly science fiction) A feature of a system whereby it destroys itself.
AUTODESTRUCT v. to self-destruct.
BUTTERSCOTCHbutterscotch n. A hard candy made from butter, brown sugar, syrup and vanilla.
butterscotch n. A sauce or syrup made of similar ingredients.
butterscotch n. A light brown colour, like that of butterscotch candy.
CONSTITUTERSconstituters n. Plural of constituter.
CONSTITUTER n. one who constitutes.
COUNTERSTATEcounterstate n. A geopolitical state that opposes another, or is set up to challenge its authority.
counterstate v. To utter a counterstatement; to deliver an opposing reply.
COUNTERSTATE v. to state in opposition.
MUTTERATIONSmutterations n. Plural of mutteration.
MUTTERATION n. (Richardson) complaining.
OUTSTRETCHEDoutstretched adj. Extended or stretched out.
outstretched v. Simple past tense and past participle of outstretch.
OUTSTRETCH v. to stretch out.
OUTSTRETCHESoutstretches v. Third-person singular simple present indicative form of outstretch.
OUTSTRETCH v. to stretch out.
RECONSTITUTEreconstitute v. (Transitive) to construct something anew, or in a different manner.
reconstitute v. (Transitive) to add liquid to a concentrated or dehydrated food to return it to its original consistency.
RECONSTITUTE v. to constitute again.
RESTITUTIONSrestitutions n. Plural of restitution.
RESTITUTION n. a restoration of something to its rightful owner.
STERNUTATIONsternutation n. (Medicine, archaic) A sneeze; sneezing, especially as a symptom.
STERNUTATION n. the act of sneezing.
STERNUTATORSsternutators n. Plural of sternutator.
STERNUTATOR n. a substance which causes sneezing, also STERNUTATIVE, STERNUTATORY.
STERNUTATORYsternutatory adj. That causes or induces sneezing; sternutative.
sternutatory n. Any substance that causes sneezing; a sternutator.
STERNUTATORY n. a substance which causes sneezing, also STERNUTATIVE, STERNUTATOR.
STONECUTTERSstonecutters n. Plural of stonecutter.
STONECUTTER n. one who cuts stone.
STOUTHEARTEDstouthearted adj. Brave, courageous and plucky.
stouthearted adj. Stubborn, resolute.
stout-hearted adj. Alternative form of stouthearted.
SUSTENTATORSsustentators n. Plural of sustentator.
SUSTENTATOR n. a sustaining part or structure.
TERATOMATOUSteratomatous adj. Relating to a teratoma.
TERATOMATOUS adj. of or like a teratoma.
TETRAPTEROUStetrapterous adj. (Entomology) Having four (two pairs of) wings.
TETRAPTEROUS adj. having four wings, also TETRAPTERAN.
TORTUOSITIEStortuosities n. Plural of tortuosity.
TORTUOSITY n. the state of being tortuous.

Scrabble words — in black are valid world wide — in RED are not valid in North America — in GREEN are valid only in North America.
Definitions are short excerpt from the WikWik.org and 1Word.ws.

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See this list for:

  • English Wiktionary: 73 words
  • Scrabble in French: 33 words
  • Scrabble in Spanish: 9 words
  • Scrabble in Italian: 48 words
  • Scrabble in German: no word
  • Scrabble in Romanian: 29 words


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