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There are 20 words containing E, N, 2P, R, S and 2U

IMMUNOSUPPRESSimmunosuppress v. (Transitive) To cause immunosuppression in.
IMMUNOSUPPRESS v. to inhibit the body's immune response.
NONPURPOSEFULnonpurposeful adj. Not purposeful.
PERSPICUOUSNESSperspicuousness n. The state or characteristic of being perspicuous; perspicuity.
PERSPICUOUSNESS n. the state of being perspicuous.
PURPOSEFULNESSpurposefulness n. The state of being purposeful.
PURPOSEFUL n. showing purpose.
SUPERCOMPUTINGsupercomputing n. (Computing) The design and use of supercomputers.
SUPERCOMPUTING n. computing using a supercomputer, a large very fast mainframe used esp. for scientific computations.
SUPERCOMPUTINGSSUPERCOMPUTING n. computing using a supercomputer, a large very fast mainframe used esp. for scientific computations.
UNDERSUPPLIEDundersupplied v. Simple past tense and past participle of undersupply.
UNDERSUPPLY v. to supply too little.
UNDERSUPPLIESundersupplies v. Third-person singular simple present indicative form of undersupply.
UNDERSUPPLY v. to supply too little.
UNDERSUPPLYundersupply v. To provide with insufficient supplies; to supply inadequately.
undersupply n. An inadequate supply.
UNDERSUPPLY v. to supply too little.
UNDERSUPPLYINGundersupplying v. Present participle of undersupply.
UNDERSUPPLY v. to supply too little.
UNPOPULARITIESunpopularities n. Plural of unpopularity.
UNPOPULARITY n. the state of being unpopular.
UNPRESUMPTUOUSunpresumptuous adj. Not presumptuous; modest.
UNPRESUMPTUOUS adj. not presumptuous.
UNPROSPEROUSunprosperous adj. Not prosperous.
UNPROSPEROUS adj. not prosperous.
UNPROSPEROUSLYunprosperously adv. In an unprosperous manner.
UNPROSPEROUS adv. not prosperous.
UNPURPOSEDunpurposed adj. Without purpose.
unpurposed adj. Not deliberate.
UNPURPOSED adj. without a purpose.
UNSUPPORTABLEunsupportable adj. Not able to be supported or endured.
UNSUPPORTABLE adj. not supportable.
UNSUPPORTEDunsupported adj. Without physical support.
unsupported adj. For which support or help is not available.
unsupported adj. Without confirmation from a credible source, without verifying support.
UNSUPPORTEDLYunsupportedly adv. Without support.
UNSUPPORTED adv. not supported.
UNSUPPORTIVEunsupportive adj. Not supportive.
UNSUPPRESSEDunsuppressed adj. Not suppressed.
UNSUPPRESSED adj. not suppressed.

Scrabble words — in black are valid world wide — in RED are not valid in North America — in GREEN are valid only in North America.
Definitions are short excerpt from the WikWik.org and 1Word.ws.

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