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There are 18 fifteen-letter words containing E, L, P, R, 2S, U and Y

DISRESPECTFULLYdisrespectfully adv. In a disrespectful manner; with a lack of respect.
DISRESPECTFUL adv. showing a lack of respect.
HYDROCEPHALUSEShydrocephaluses n. Plural of hydrocephalus.
HYDROCEPHALUS n. an accumulation of serous fluid within the cranial cavity, also HYDROCEPHALY.
HYPERINSULINISMhyperinsulinism n. Hyperinsulinemia.
HYPERINSULINISM n. the presence of excess insulin in the body resulting in hypoglycemia.
HYPERSTIMULATEShyperstimulates v. Third-person singular simple present indicative form of hyperstimulate.
HYPERSTIMULATE v. to stimulate excessively.
NEUROSYPHILISESNEUROSYPHILIS n. a syphilitic infection affecting the central nervous system.
PERSPICACIOUSLYperspicaciously adv. With the power of seeing or understanding clearly; quick-sightedly; with sharp of sight.
perspicaciously adv. (Figurative) With acute discernment; keenly; with mental perception.
PERSPICACIOUS adv. clear-minded; astute; perceptive.
POLYUNSATURATESpolyunsaturates n. Plural of polyunsaturate.
POLYUNSATURATE n. a fat that is polyunsaturated.
PRAYERFULNESSESPRAYERFULNESS n. PRAYERFUL, given to prayer.
SCULPTURESQUELYsculpturesquely adv. In a sculpturesque manner.
SCULPTURESQUE adv. done in the manner of or resembling sculpture.
SERENDIPITOUSLYserendipitously adv. By serendipity; by blind luck in combination with wisdom; by fortunate accident.
SERENDIPITOUS adv. obtained or characterized by serendipity.
SPLENDIFEROUSLYsplendiferously adv. In a splendiferous manner.
SPLENDIFEROUS adv. splendid.
SUBREPTITIOUSLYsubreptitiously adv. Obsolete form of surreptitiously.
SUBREPTITIOUS adv. fraudulently obtained; surreptitious.
SULFINPYRAZONESsulfinpyrazones n. Plural of sulfinpyrazone.
SULFINPYRAZONE n. a uricosuric drug used in the long-term treatment of chronic gout.
SUPERPLASTICITYsuperplasticity n. The deformation of a solid beyond its normal breaking point.
SUPERPLASTICITY n. the state of being superplastic.
SUPERSTITIOUSLYsuperstitiously adv. In a superstitious manner.
SUPERSTITIOUS adv. relating to superstition.
SUPPRESSIBILITYsuppressibility n. Quality of being suppressible.
SUPPRESSIBILITY n. the state of being suppressible.
SURREPTITIOUSLYsurreptitiously adv. In a surreptitious manner; stealthily, furtively, secretly.
SURREPTITIOUS adv. done by stealth.
UNPROGRESSIVELYunprogressively adv. In an unprogressive way.
UNPROGRESSIVE adv. not progressive.

Scrabble words — in black are valid world wide — in RED are not valid in North America — in GREEN are valid only in North America.
Definitions are short excerpt from the 1Word.ws and WikWik.org.

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See this list for:

  • English Wiktionary: 70 words
  • Scrabble in French: 9 words
  • Scrabble in Spanish: no word
  • Scrabble in Italian: no word
  • Scrabble in German: no word
  • Scrabble in Romanian: no word


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