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There are 15 twelve-letter words containing E, I, O, 2S, T, U and Y

ABSTEMIOUSLYabstemiously adv. Marked by abstinence or restraint, especially in relation to food or drink.
ABSTEMIOUS adv. sparing, esp. in matters of eating and drinking.
BOISTEROUSLYboisterously adv. In a boisterous manner.
BOISTEROUS adv. rowdy, high-spirited.
COUNTRYSIDEScountrysides n. Plural of countryside.
country-sides n. Plural of country-side.
COUNTRYSIDE n. a rural area.
DESPITEOUSLYdespiteously adv. In a despiteous manner.
DESPITEOUS adv. (obsolete) feeling or showing despite.
DISPITEOUSLYdispiteously adv. In a dispiteous manner.
DISPITEOUS adv. (obsolete) pitiless, malicious.
INCESTUOUSLYincestuously adv. In an incestuous manner.
INCESTUOUS adv. constituting or involving incest.
ISOBUTYLENESisobutylenes n. Plural of isobutylene.
ISOBUTYLENE n. an isomer of butylene used in the manufacture of synthetic rubber.
LEUCOCYTOSISleucocytosis n. (Pathology) A raised white blood cell count, above the normal range.
LEUCOCYTOSIS n. an increase in the number of leucocytes in blood.
LEUKOCYTOSISleukocytosis n. Alternative spelling of leucocytosis.
LEUKOCYTOSIS n. an increase in the number of white blood cells in the circulating blood.
MULTISENSORYmultisensory adj. Pertaining to the integration of information from different sensory modalities.
MULTISENSORY adj. relating to or involving several physiological senses.
MULTISTOREYSmultistoreys n. Plural of multistorey.
multi-storeys n. Plural of multi-storey.
MULTISTOREY n. a multistorey car park.
MYSTERIOUSLYmysteriously adv. In a mysterious manner.
MYSTERIOUS adv. of, relating to, or constituting mystery.
PNEUMOCYSTISpneumocystis n. (Pathology) A parasitic fungal organism of the genus Pneumocystis, in humans specifically Pneumocystis jorevicii.
Pneumocystis prop.n. A taxonomic genus within the family Pneumocystidaceae – fungi first thought to be protozoa, including…
PNEUMOCYSTIS n. any protozoan of the genus Pneumocystis, esp. P. carinii, which is a cause of pneumonia.
PYROSULFITESpyrosulfites n. Plural of pyrosulfite.
PYROSULFITE n. as in sodium pyrosulfite, an inorganic compound used as a preservative, antioxidant and disinfectant.
ROISTEROUSLYroisterously adv. In a roisterous way.
ROISTEROUS adv. blustering, boisterous, also ROYSTEROUS.

Scrabble words — in black are valid world wide — in RED are not valid in North America — in GREEN are valid only in North America.
Definitions are short excerpt from the WikWik.org and 1Word.ws.

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See this list for:

  • English Wiktionary: 54 words
  • Scrabble in French: 14 words
  • Scrabble in Spanish: 14 words
  • Scrabble in Italian: no word
  • Scrabble in German: no word
  • Scrabble in Romanian: no word


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