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There are 12 twelve-letter words containing E, 2I, 2O, 2P and S

EPIMORPHOSISepimorphosis n. The regeneration of tissues or organs through the dedifferentiation of existing, differentiated adult tissues.
EPIMORPHOSIS n. a type of development in animals, such as certain insect larvae, in which segmentation of the body is complete before hatching.
HYPOPLOIDIEShypoploidies n. Plural of hypoploidy.
HYPOPLOIDY n. the state of being hypoploid, having a chromosome number a few below the normal diploid number.
LIPOPROTEINSlipoproteins n. Plural of lipoprotein.
LIPOPROTEIN n. a water-soluble protein found in the blood, which carries cholesterol.
PHILOSOPHIESphilosophies n. Plural of philosophy.
PHILOSOPHY n. all learning exclusive of technical precepts and practical arts.
PHILOSOPHISEphilosophise v. (UK, Australia, New Zealand) Alternative spelling of philosophize.
PHILOSOPHISE v. to reason in the manner of a philosopher, also PHILOSOPHIZE.
PHILOSOPHIZEphilosophize v. To ponder or reason out philosophically.
PHILOSOPHIZE v. to reason in the manner of a philosopher, also PHILOSOPHISE.
PHOTOPHILIESPHOTOPHILY n. the state of being photophilic, light-loving, turning towards the light.
PLEIOTROPIESpleiotropies n. Plural of pleiotropy.
PLEIOTROPY n. the property of having an effect simultaneously on more than one characteristic of the offspring.
PLEIOTROPISMpleiotropism n. (Genetics) pleiotropy.
PLEIOTROPISM n. the state of being pleiotropic, having an effect simultaneously on more than one character in the offspring.
POLYPLOIDIESpolyploidies n. Plural of polyploidy.
POLYPLOIDY n. the condition of being polyploid.
POSTPOSITIVEpostpositive adj. (Grammar, of an adjective or other modifier) Placed after the word modified, either immediately after…
postpositive n. (Grammar) A postpositive modifier.
POSTPOSITIVE adj. of an adjective, placed after the word it modifies e.g. attorney general, Scrabble player manque.
PREPOSITIONSprepositions n. Plural of preposition.
prepositions v. Third-person singular simple present indicative form of preposition.
PREPOSITION n. a function word that typically combines with a noun phrase to form a phrase which usually expresses a modification or predication.

Scrabble words — in black are valid world wide — in RED are not valid in North America — in GREEN are valid only in North America.
Definitions are short excerpt from the WikWik.org and 1Word.ws.

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See this list for:

  • English Wiktionary: 40 words
  • Scrabble in French: 12 words
  • Scrabble in Spanish: 7 words
  • Scrabble in Italian: 26 words
  • Scrabble in German: no word
  • Scrabble in Romanian: 28 words


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