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There are 8 twelve-letter words containing E, 2I, L, 2R, S and Y

IRREMISSIBLYirremissibly adv. In an irremissible manner; unpardonably.
IRREMISSIBLE adv. unpardonable.
IRRESISTABLYirresistably adv. Dated form of irresistibly.
IRRESISTIBLYirresistibly adv. In an irresistible manner.
IRRESISTIBLE adv. impossible to resist.
IRREVERSIBLYirreversibly adv. In an irreversible manner.
IRREVERSIBLE adv. not reversible.
LITERARYISMSliteraryisms n. Plural of literaryism.
LITERARYISM n. a bookish expression.
PERSPIRINGLYperspiringly adv. While perspiring; with perspiration or sweat.
PERSPIRING adv. PERSPIRE, to exude sweat through the pores of the skin.
PYRROLIDINESpyrrolidines n. Plural of pyrrolidine.
PYRROLIDINE n. a colourless strongly alkaline heterocyclic base both occurring naturally and produced from pyrrole.
SUPERCILIARYsuperciliary adj. (Anatomy) Of or pertaining to the supercilium or eyebrow.
superciliary n. (Zoology) A distinct streak of colour above the eyes, as in some birds.
SUPERCILIARY adj. of, on or near the eyebrow.

Scrabble words — in black are valid world wide — in RED are not valid in North America — in GREEN are valid only in North America.
Definitions are short excerpt from the WikWik.org and 1Word.ws.

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See this list for:

  • English Wiktionary: 24 words
  • Scrabble in French: 3 words
  • Scrabble in Spanish: no word
  • Scrabble in Italian: no word
  • Scrabble in German: no word
  • Scrabble in Romanian: 1 word


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