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There are 20 twelve-letter words containing E, F, 2I, R, 2S and T

DISCOMFITERSDISCOMFITER n. one who discomfits.
DISFORESTINGdisforesting v. Present participle of disforest.
DISFOREST v. to clear of forest, also DISAFFOREST.
DISINFECTORSdisinfectors n. Plural of disinfector.
DISINFECTOR n. an agent that disinfects.
FALDISTORIESfaldistories n. Plural of faldistory.
FALDISTORY n. (obsolete) the throne or seat of a bishop within the chancel.
FIBROSITISESFIBROSITIS n. inflammation of the nerve fibres.
FINASTERIDESSorry, definition not available.
FLOURISHIESTFLOURISHY adj. full of flourishes.
FRACTIONISESfractionises v. Third-person singular simple present indicative form of fractionise.
FRACTIONISE v. to break up into fractions, also FRACTIONIZE.
FRENETICISMSfreneticisms n. Plural of freneticism.
FRENETICISM n. the state of being frenetic.
FRICTIONLESSfrictionless adj. Of or pertaining to lack of friction.
frictionless adj. (Finance) Of a transaction or trade, without tariffs and non-tariff barriers.
FRICTIONLESS adj. without friction.
FRUITINESSESFRUITINESS n. the state of being fruity.
GUITARFISHESguitarfishes n. Plural of guitarfish.
GUITARFISH n. a kind of ray, somewhat guitar-like in shape.
INFORMATISESinformatises v. Third-person singular simple present indicative form of informatise.
INFORMATISE v. to convert (something) into data or information, esp. for analysis, processing, or consumption by computers, also INFORMATIZE.
INTENSIFIERSintensifiers n. Plural of intensifier.
INTENSIFIER n. one that intensifies.
INTERFUSIONSinterfusions n. Plural of interfusion.
INTERFUSION n. the act of interfusing.
KITESURFINGSKITESURFING n. the sport of surfing while towed by a kite.
PERFUSIONISTperfusionist n. A trained clinician who operates the heart-lung machine during cardiac and other surgeries.
PERFUSIONIST n. the member of a surgical team administering continuous blood transfusion.
PREFEMINISTSSorry, definition not available.
RABBITFISHESrabbitfishes n. Plural of rabbitfish.
RABBITFISH n. a type of herring, or other fish thought to resemble a rabbit.
TRIFLINGNESStriflingness n. The state or quality of being trifling.
TRIFLINGNESS n. the state of being trifling.

Scrabble words — in black are valid world wide — in RED are not valid in North America — in GREEN are valid only in North America.
Definitions are short excerpt from the 1Word.ws and WikWik.org.

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