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There are 12 words containing 2E, M, 2P, 2R and U

PUERPERIUMpuerperium n. (Obstetrics) The period of time lasting around a month immediately following childbirth, when the mother’s…
PUERPERIUM n. (Latin) the condition immediately following childbirth.
PRECOMPUTERprecomputer adj. Before the availability of computer technology.
precomputer n. A device used for calculation before the development of computers.
PRECOMPUTER adj. belonging to the era before computers.
PERINEPHRIUMPERINEPHRIUM n. the fatty tissue surrounding the kidney.
PRECOMPUTERSprecomputers adv. (Informal) Before the availability of computers.
precomputers n. Plural of precomputer.
SUPERPOLYMERsuperpolymer n. (Chemistry, dated) Any aliphatic polyester.
SUPERPOLYMER n. a superior polymer.
SUPERPREMIUMsuperpremium adj. Of greatly superior quality, beyond premium.
superpremium n. A product or brand of greatly superior quality, beyond premium.
SUPERPREMIUM n. a very large premium.
SUPERCOMPUTERsupercomputer n. (Computing) Any computer that has a far greater processing power than others of its generation; typically…
SUPERCOMPUTER n. a large very fast mainframe used esp. for scientific computations.
SUPERPOLYMERSsuperpolymers n. Plural of superpolymer.
SUPERPOLYMER n. a superior polymer.
SUPERPREMIUMSsuperpremiums n. Plural of superpremium.
SUPERPREMIUM n. a very large premium.
MERCAPTOPURINEmercaptopurine n. (Pharmacology) An thiol antimetabolite C5H4N4S that interferes especially with the metabolism of purine…
MERCAPTOPURINE n. an antimetabolite sometimes used in the treatment of acute leukemia.
SUPERCOMPUTERSsupercomputers n. Plural of supercomputer.
SUPERCOMPUTER n. a large very fast mainframe used esp. for scientific computations.
MERCAPTOPURINESmercaptopurines n. Plural of mercaptopurine.
MERCAPTOPURINE n. an antimetabolite sometimes used in the treatment of acute leukemia.

Scrabble words — in black are valid world wide — in RED are not valid in North America — in GREEN are valid only in North America.
Definitions are short excerpt from the WikWik.org and 1Word.ws.

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