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There are 12 words containing 2E, M, 2O, 2S and X

COMPLEXIONLESS	• complexionless adj. Colourless; pale. • COMPLEXIONLESS adj. without a complexion.
EXOPHTHALMOSES	• exophthalmoses n. Plural of exophthalmos. • EXOPHTHALMOS n. abnormal protrusion of the eyeball, also EXOPHTHALMUS.
EXOSMOSE	• exosmose n. Archaic form of exosmosis. • EXOSMOSE n. osmosis outwards, i.e. away from the solution, also EXOSMOSIS.
EXOSMOSES	• exosmoses n. Plural of exosmosis. • EXOSMOSE n. osmosis outwards, i.e. away from the solution, also EXOSMOSIS.
EXPOSOMES	• exposomes n. Plural of exposome. • EXPOSOME n. a collection of environmental factors, such as stress and diet, to which an individual is exposed and which can have an effect on health.
HOMOSEXES	• homosexes n. Plural of homosex. • HOMOSEX n. (short for) homosexuality.
HOMOSEXUALITIES	• homosexualities n. Plural of homosexuality. • HOMOSEXUALITY n. the state of being homosexual.
MESOTHORAXES	• mesothoraxes n. Plural of mesothorax. • MESOTHORAX n. the middle segment of the thorax in insects.
PEROXISOMES	• peroxisomes n. Plural of peroxisome. • PEROXISOME n. an organelle containing enzymes.
SEROTAXONOMIES	• SEROTAXONOMY n. serological analysis as a source of information for taxonomic classification.
SEXTODECIMOS	• sextodecimos n. Plural of sextodecimo. • SEXTODECIMO n. a book size 5 5/8 in. x 4 3/8 in. (abbreviated as 16mo.), also SIXTEENMO.
SMOKEBOXES	• smokeboxes n. Plural of smokebox. • SMOKEBOX n. part of a steam boiler where the smoke is collected before passing out at the chimney.

Scrabble words — in black are valid world wide — in RED are not valid in North America — in GREEN are valid only in North America.
Definitions are short excerpt from the 1Word.ws and WikWik.org.

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English Wiktionary: 164 words
Scrabble in French: 11 words
Scrabble in Spanish: 79 words
Scrabble in Italian: no word
Scrabble in German: no word
Scrabble in Romanian: no word

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