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There are 13 words containing 2E, L, 2N, 2P and R

PREPLANNEDpreplanned v. Simple past tense and past participle of preplan.
preplanned adj. Planned in advance.
PREPLAN v. to plan in advance.
UNPERPLEXINGunperplexing adj. Not perplexing.
unperplexing v. Present participle of unperplex.
UNPERPLEX v. to free from perplexity.
PARENCEPHALONparencephalon n. (Anatomy) The cerebellum.
PARENCEPHALON n. a cerebral hemisphere.
PHENYLEPHRINEphenylephrine n. (Medicine, pharmacology) An α-adrenergic receptor agonist related to adrenaline, used as a vasoconstrictor…
PHENYLEPHRINE n. an agent used in the form of its hydrochloride as a vasoconstrictor.
PARALEIPOMENONPARALEIPOMENON n. a thing added as a supplement to a main text, also PARALIPOMENON.
PHENYLEPHRINESphenylephrines n. Plural of phenylephrine.
PHENYLEPHRINE n. an agent used in the form of its hydrochloride as a vasoconstrictor.
PREPONDERANTLYpreponderantly adv. In a preponderant manner.
PREPONDERANT adv. having superior weight, force, or influence.
PROSENCEPHALONprosencephalon n. (Neuroanatomy) Forebrain.
PROSENCEPHALON n. the forebrain.
INAPPREHENSIBLEinapprehensible adj. That cannot be apprehended; not apprehensible to or graspable by either body or mind.
INAPPREHENSIBLE adj. not capable of being apprehended.
PLENIPOTENTIARYplenipotentiary n. A person invested with full powers, especially as the diplomatic agent of a sovereign state, (originally)…
plenipotentiary adj. Invested with full power.
plenipotentiary adj. Of or relating to a plenipotentiary agent.
PLEUROPNEUMONIApleuropneumonia n. (Pathology) inflammation of the pleura and lungs; a combination of pleurisy and pneumonia, especially…
PLEUROPNEUMONIA n. pneumonia aggravated by pleurisy.
PRINCIPALNESSESPRINCIPALNESS n. the state of being principal.
UNAPPREHENSIBLEunapprehensible adj. Alternative form of inapprehensible.
UNAPPREHENSIBLE adj. not apprehensible.

Scrabble words — in black are valid world wide — in RED are not valid in North America — in GREEN are valid only in North America.
Definitions are short excerpt from the WikWik.org and 1Word.ws.

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