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There are 19 words containing E, M, 2P, S and 2U

PUMPHOUSEpumphouse n. A building containing pumping equipment; thus…
pump␣house n. Alternative form of pumphouse.
PUMPHOUSE n. a building in which are housed pumps that supply e.g. an irrigation system.
MUDPUPPIESmudpuppies n. Plural of mudpuppy.
mud␣puppies n. Plural of mud puppy.
MUDPUPPY n. a large salamander, the axolotl.
PUMPHOUSESpumphouses n. Plural of pumphouse.
pump␣houses n. Plural of pump house.
PUMPHOUSE n. a building in which are housed pumps that supply e.g. an irrigation system.
SUPERPHYLUMsuperphylum n. (Taxonomy) A taxonomic category above phylum and below subkingdom.
SUPERPHYLUM n. a taxonomical division above phylum.
SUPPEDANEUMsuppedaneum n. A foot-support for a crucified person, projecting from the base of the cross.
suppedaneum n. The platform in front of the altar on which celebrating priest stands.
SUPPEDANEUM n. a support under the foot of a crucified person.
MULTIPURPOSEmultipurpose adj. Designed or intended to fit more than one type of function or application; having multiple uses.
multi-purpose adj. Alternative form of multipurpose.
MULTIPURPOSE adj. having many purposes.
PRESUMPTUOUSpresumptuous adj. Going beyond what is right, proper, or appropriate because of an excess of self-confidence or arrogance.
PRESUMPTUOUS adj. overstepping due bounds (as of propriety or courtesy).
PSEUDOPODIUMpseudopodium n. (Cytology) pseudopod.
PSEUDOPODIUM n. a process protruding from the cell of a protozoan, etc., used for movement or feeding.
SUPERPREMIUMsuperpremium adj. Of greatly superior quality, beyond premium.
superpremium n. A product or brand of greatly superior quality, beyond premium.
SUPERPREMIUM n. a very large premium.
MULTIPURPOSESSorry, definition not available.
SUPERCOMPUTERsupercomputer n. (Computing) Any computer that has a far greater processing power than others of its generation; typically…
SUPERCOMPUTER n. a large very fast mainframe used esp. for scientific computations.
SUPERPREMIUMSsuperpremiums n. Plural of superpremium.
SUPERPREMIUM n. a very large premium.
IMMUNOSUPPRESSimmunosuppress v. (Transitive) To cause immunosuppression in.
IMMUNOSUPPRESS v. to inhibit the body's immune response.
PRESUMPTUOUSLYpresumptuously adv. In a presumptuous manner; arrogantly.
PRESUMPTUOUS adv. overstepping due bounds (as of propriety or courtesy).
PSEUDOMORPHOUSpseudomorphous adj. Not having the true form.
PSEUDOMORPHOUS adj. of or like a pseudomorph, also PSEUDOMORPHIC.
SUPERCOMPUTERSsupercomputers n. Plural of supercomputer.
SUPERCOMPUTER n. a large very fast mainframe used esp. for scientific computations.
SUPERCOMPUTINGsupercomputing n. (Computing) The design and use of supercomputers.
SUPERCOMPUTING n. computing using a supercomputer, a large very fast mainframe used esp. for scientific computations.
UNPRESUMPTUOUSunpresumptuous adj. Not presumptuous; modest.
UNPRESUMPTUOUS adj. not presumptuous.
SUPERCOMPUTINGSSUPERCOMPUTING n. computing using a supercomputer, a large very fast mainframe used esp. for scientific computations.

Scrabble words — in black are valid world wide — in RED are not valid in North America — in GREEN are valid only in North America.
Definitions are short excerpt from the WikWik.org and 1Word.ws.

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