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There are 18 words containing E, I, O, 2P and 2U

PUPIGEROUSpupigerous adj. Containing a pupa.
PUPIGEROUS adj. bearing a puparium.
PERSPICUOUSperspicuous adj. Clearly expressed, easy to understand; lucid.
perspicuous adj. (Logic) Of a language or notation, such as that of formal propositional calculus: where the process…
perspicuous adj. (Rare) Transparent; translucent.
MULTIPURPOSEmultipurpose adj. Designed or intended to fit more than one type of function or application; having multiple uses.
multi-purpose adj. Alternative form of multipurpose.
MULTIPURPOSE adj. having many purposes.
PAPULIFEROUSpapuliferous adj. Pimply; covered with papulae.
PAPULIFEROUS adj. pimply.
PSEUDOPODIUMpseudopodium n. (Cytology) pseudopod.
PSEUDOPODIUM n. a process protruding from the cell of a protozoan, etc., used for movement or feeding.
UNSUPPORTIVEunsupportive adj. Not supportive.
LIPOSCULPTUREliposculpture n. A form of liposuction that uses ultrasound to first break up the fat.
LIPOSCULPTURE n. cosmetic surgery on the lips.
MULTIPURPOSESSorry, definition not available.
PERSPICUOUSLYperspicuously adv. With clarity and lucidity.
PERSPICUOUS adv. easily understood; clearly expressed.
UNPREOCCUPIEDunpreoccupied adj. Not preoccupied.
UNPREOCCUPIED adj. not preoccupied.
IMMUNOSUPPRESSimmunosuppress v. (Transitive) To cause immunosuppression in.
IMMUNOSUPPRESS v. to inhibit the body's immune response.
LIPOSCULPTURESLIPOSCULPTURE n. cosmetic surgery on the lips.
SUPERCOMPUTINGsupercomputing n. (Computing) The design and use of supercomputers.
SUPERCOMPUTING n. computing using a supercomputer, a large very fast mainframe used esp. for scientific computations.
UNPOPULARITIESunpopularities n. Plural of unpopularity.
UNPOPULARITY n. the state of being unpopular.
PEROXYSULPHURICPEROXYSULPHURIC adj. as in peroxysulphuric acid.
PERSPICUOUSNESSperspicuousness n. The state or characteristic of being perspicuous; perspicuity.
PERSPICUOUSNESS n. the state of being perspicuous.
PLEUROPNEUMONIApleuropneumonia n. (Pathology) inflammation of the pleura and lungs; a combination of pleurisy and pneumonia, especially…
PLEUROPNEUMONIA n. pneumonia aggravated by pleurisy.
SUPERCOMPUTINGSSUPERCOMPUTING n. computing using a supercomputer, a large very fast mainframe used esp. for scientific computations.

Scrabble words — in black are valid world wide — in RED are not valid in North America — in GREEN are valid only in North America.
Definitions are short excerpt from the WikWik.org and 1Word.ws.

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