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There are 20 words containing E, H, 2I, 2S and X

SIXTIETHSsixtieths n. Plural of sixtieth.
SIXTIETH n. one of sixty equal parts.
PHOENIXISMSPHOENIXISM n. the practice of forming a new company with same directors, workforce etc. from a bankrupt company.
EXTINGUISHESextinguishes v. Third-person singular simple present indicative form of extinguish.
EXTINGUISH v. to bring to an end.
VIXENISHNESSvixenishness n. The state or condition of being vixenish.
VIXENISHNESS n. the state of being vixenish.
EXAMINERSHIPSexaminerships n. Plural of examinership.
EXAMINERSHIP n. the office of examiner.
EXTINGUISHERSextinguishers n. Plural of extinguisher.
EXTINGUISHER n. a device that extinguishes.
PHOTOOXIDISESPHOTOOXIDISE v. to undergo photooxidation, also PHOTOOXIDIZE.
SEXTILLIONTHSsextillionths n. Plural of sextillionth.
SEXTILLIONTH n. the ordinal of a sextillion, a thousand raised to the seventh power.
XIPHISTERNUMSxiphisternums n. Plural of xiphisternum.
XIPHISTERNUM n. the posterior and smallest of the three divisions of the sternum.
EXHAUSTIVITIESexhaustivities n. Plural of exhaustivity.
EXHAUSTIVITY n. the state of being exhaustive.
EXHIBITIONISMSexhibitionisms n. Plural of exhibitionism.
EXHIBITIONISM n. extravagant behaviour aimed at drawing attention to oneself.
EXHIBITIONISTSexhibitionists n. Plural of exhibitionist.
EXHIBITIONIST n. one who engages in exhibitionism.
EXTINGUISHANTSextinguishants n. Plural of extinguishant.
EXTINGUISHANT n. a substance used to extinguish fires.
HEXOSAMINIDASEhexosaminidase n. (Biochemistry) Any enzyme that catalyzes the hydrolysis of terminal hexosamine residues in hexosaminides.
HEXOSAMINIDASE n. either of two hydrolytic enzymes that catalyze the splitting off of a hexose from a ganglioside and are deficient in some metabolic diseases.
VIXENISHNESSESVIXENISHNESS n. the state of being vixenish.
EXTINGUISHMENTSextinguishments n. Plural of extinguishment.
EXTINGUISHMENT n. the act of extinguishing.
HEXOSAMINIDASEShexosaminidases n. Plural of hexosaminidase.
HEXOSAMINIDASE n. either of two hydrolytic enzymes that catalyze the splitting off of a hexose from a ganglioside and are deficient in some metabolic diseases.
HIERACOSPHINXEShieracosphinxes n. Plural of hieracosphinx.
HIERACOSPHINX n. in ancient Egyptian art, a hawk-headed sphinx.
HOMOSEXUALITIEShomosexualities n. Plural of homosexuality.
HOMOSEXUALITY n. the state of being homosexual.
LEXICOGRAPHISTSlexicographists n. Plural of lexicographist.
LEXICOGRAPHIST n. one who makes dictionaries.

Scrabble words — in black are valid world wide — in RED are not valid in North America — in GREEN are valid only in North America.
Definitions are short excerpt from the 1Word.ws and WikWik.org.

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