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There are 18 words containing E, 2F, 2I, O and U

EFFICACIOUSefficacious adj. (Formal) Effective; possessing efficacy.
EFFICACIOUS adj. having the power to produce a desired effect.
EFFICACIOUSLYefficaciously adv. In an efficacious manner.
EFFICACIOUS adv. having the power to produce a desired effect.
EFFICACIOUSNESSefficaciousness n. Quality of being efficacious.
EFFICACIOUS n. having the power to produce a desired effect.
EFFIGURATIONEFFIGURATION n. an elaborate, detailed description of an object or an event.
EFFIGURATIONSEFFIGURATION n. an elaborate, detailed description of an object or an event.
FORAMINIFEROUSforaminiferous adj. Having small openings, or foramina.
foraminiferous adj. Pertaining to, or composed of, Foraminifera.
FORAMINIFEROUS adj. bearing foramina.
FOSSILIFEROUSfossiliferous adj. Containing fossils.
FOSSILIFEROUS adj. bearing fossils.
INEFFICACIOUSinefficacious adj. Incapable of having the intended consequence.
inefficacious adj. Not effective.
INEFFICACIOUS adj. lacking the power to produce a desired effect.
INEFFICACIOUSLYinefficaciously adv. Without efficacy or effect.
INEFFICACIOUS adv. lacking the power to produce a desired effect.
INOFFICIOUSNESSinofficiousness n. The quality of being inofficious.
INOFFICIOUS n. not officious.
INTERDIFFUSIONinterdiffusion n. The mutual diffusion of two fluids, especially through a membrane.
INTERDIFFUSION n. the process of diffusing and mixing freely so as to approach a homogeneous mixture.
INTERDIFFUSIONSinterdiffusions n. Plural of interdiffusion.
INTERDIFFUSION n. the process of diffusing and mixing freely so as to approach a homogeneous mixture.
NONDIFFUSIBLEnondiffusible adj. Not diffusible.
NONDIFFUSIBLE adj. not diffusible.
OFFICIOUSNESSofficiousness n. The quality of being officious.
OFFICIOUS n. volunteering one's services too eagerly.
OFFICIOUSNESSESofficiousnesses n. Plural of officiousness.
OFFICIOUSNESS n. OFFICIOUS, volunteering one's services too eagerly.
OVERFULFILLINGoverfulfilling v. Present participle of overfulfil.
OVERFULFILL v. to fulfill to excess.
UNFORTIFIEDunfortified adj. Not fortified.
unfortified v. Simple past tense and past participle of unfortify.
UNFORTIFIED adj. not fortified.
UNFOSSILIFEROUSunfossiliferous adj. Not fossiliferous, nonfossiliferous.
UNFOSSILIFEROUS adj. not fossiliferous.

Scrabble words — in black are valid world wide — in RED are not valid in North America — in GREEN are valid only in North America.
Definitions are short excerpt from the WikWik.org and 1Word.ws.

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