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There are 13 words containing 2E, P, 3S and Z

DEPRESSURIZESdepressurizes v. Third-person singular simple present indicative form of depressurize.
DEPRESSURIZE v. to reduce the air pressure in esp. suddenly, also DEPRESSURISE.
HAPHAZARDNESSESHAPHAZARDNESS n. HAPHAZARD, marked by lack of plan, order, or direction.
HYPERSENSITIZEShypersensitizes v. Third-person singular simple present indicative form of hypersensitize.
HYPERSENSITIZE v. to make hypersensitive, also HYPERSENSITISE.
HYPOSENSITIZEShyposensitizes v. Third-person singular simple present indicative form of hyposensitize.
HYPOSENSITIZE v. to lower the sensitivity of, also HYPOSENSITISE.
MISEMPHASIZESmisemphasizes v. Third-person singular simple present indicative form of misemphasize.
MISEMPHASIZE v. to emphasize wrongly, also MISEMPHASISE.
PHOTOSENSITIZESphotosensitizes v. Third-person singular simple present indicative form of photosensitize.
PHOTOSENSITIZE v. to make photosensitive by chemical or other means, also PHOTOSENSITISE.
PRESSURIZERSpressurizers n. Plural of pressurizer.
PRESSURIZER n. an apparatus for pressurizing, also PRESSURISER.
PRESSURIZESpressurizes v. Third-person singular simple present indicative form of pressurize.
PRESSURIZE v. to place under pressure, also PRESSURISE.
REPRESSURIZESrepressurizes v. Third-person singular simple present indicative form of repressurize.
REPRESSURIZE v. to pressurize again, also REPRESSURISE.
SPETSNAZESSPETSNAZ n. (Russian) a select military unit in the former Soviet Union, also SPETZNAZ.
SUBSPECIALIZESsubspecializes v. Third-person singular simple present indicative form of subspecialize.
SUBSPECIALIZE v. to practise a subspecialty, also SUBSPECIALISE.
SUPERSIZESsupersizes v. Third-person singular simple present indicative form of supersize.
SUPERSIZE v. to increase the size of.
ZIPPINESSESZIPPINESS n. the quality of being zippy.

Scrabble words — in black are valid world wide — in RED are not valid in North America — in GREEN are valid only in North America.
Definitions are short excerpt from the 1Word.ws and WikWik.org.

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