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There are 17 words containing 2E, 2P, 2R and X

PERPLEXERperplexer n. One who perplexes.
PERPLEXER n. one who perplexes.
PERPLEXERSperplexers n. Plural of perplexer.
PERPLEXER n. one who perplexes.
EXPROPRIATEexpropriate v. (Transitive) To deprive a person of (their private property) for public use.
EXPROPRIATE v. to deprive of possession or proprietary rights.
EXPROPRIABLEexpropriable adj. Capable of being expropriated, or seized for public use.
EXPROPRIABLE adj. that can be expropriated.
EXPROPRIATEDexpropriated v. Simple past tense and past participle of expropriate.
EXPROPRIATE v. to deprive of possession or proprietary rights.
EXPROPRIATESexpropriates v. Third-person singular simple present indicative form of expropriate.
EXPROPRIATE v. to deprive of possession or proprietary rights.
HYPERPYREXIAhyperpyrexia n. (Medicine) An excessive and unusual elevation of set body temperature greater than or equal to 41°C…
HYPERPYREXIA n. an extremely high fever, with a temperature of 41 degrees Centigrade or above, also HYPERTHERMY.
SUPEREXPRESSsuperexpress n. A very fast express train.
SUPEREXPRESS n. a very fast express.
HYPERPROSEXIAhyperprosexia n. (Medicine, rare) Excessive attention; an abnormal state in which a person concentrates on one thing…
HYPERPROSEXIA n. abnormal powers of perception, as in Australian aboriginal trackers.
HYPERPYREXIALhyperpyrexial adj. Exhibiting or relating to hyperpyrexia.
HYPERPYREXIAL adj. showing hyperpyrexia, an extremely high fever.
HYPERPYREXIAShyperpyrexias n. Plural of hyperpyrexia.
HYPERPYREXIA n. an extremely high fever, with a temperature of 41 degrees Centigrade or above, also HYPERTHERMY.
PREEXPERIMENTpreexperiment adj. Before an experiment takes place.
preexperiment n. A simple form of research that examines a group or groups before and after an event, to see whether…
PREEXPERIMENT adj. preceding an experiment.
PROPRIETRIXESproprietrixes n. Plural of proprietrix.
PROPRIETRIX n. a female proprietor, also PROPRIETRESS.
HYPERPROSEXIASHYPERPROSEXIA n. abnormal powers of perception, as in Australian aboriginal trackers.
PREEXPERIMENTSpreexperiments n. Plural of preexperiment.
SUPEREXPRESSESsuperexpresses n. Plural of superexpress.
SUPEREXPRESS n. a very fast express.
PREEXPERIMENTALpreexperimental adj. Prior to an experiment.

Scrabble words — in black are valid world wide — in RED are not valid in North America — in GREEN are valid only in North America.
Definitions are short excerpt from the WikWik.org and 1Word.ws.

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