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There are 17 words containing 2E, 3O, P and U

COLEOPTEROUScoleopterous adj. Of or pertaining to beetles of the order Coleoptera.
COLEOPTEROUS adj. pertaining to beetles and weevils; having hard anterior wings.
HETEROTOPOUSheterotopous adj. Exhibiting heterotopy.
HETEROTOPOUS adj. relating to heterotopy, displacement of an organ of the body, also HETEROTOPIC.
PSEUDOCOELOMpseudocoelom n. Synonym of pseudocoel.
HETEROSPOROUSheterosporous adj. (Botany, of an organism) Producing both male and female gametophytes.
HETEROSPOROUS adj. producing two different sizes or kinds of spores.
PROLEGOMENOUSprolegomenous adj. (Literary) Introductory; functioning as a preface or prolegomenon.
PROLEGOMENOUS adj. of the nature of a prolegomenon, introduction, also PROLEGOMENAL, PROLEGOMENARY.
PSEUDOCOELOMSpseudocoeloms n. Plural of pseudocoelom.
COTEMPORANEOUScotemporaneous adj. Living or existing at the same time; contemporaneous.
COTEMPORANEOUS adj. existing, occurring, or originating during the same time, also CONTEMPORANEOUS.
HETEROMORPHOUSheteromorphous adj. (Biology) heteromorphic.
HETEROMORPHOUS adj. having different forms, also HETEROMORPHIC.
PNEUMOCONIOSESpneumoconioses n. Plural of pneumoconiosis.
PNEUMOCONIOSIS n. a disease of the lungs caused by the habitual inhalation of irritants (as mineral or metallic particles).
PNEUMOKONIOSESPNEUMOKONIOSIS n. a disease of the lungs caused by the habitual inhalation of irritants (as mineral or metallic particles).
PNEUMONOLOGIESPNEUMONOLOGY n. the study of the respiratory system.
POLEMONIACEOUSpolemoniaceous adj. Of or pertaining to the plant family Polemoniaceae.
POLEMONIACEOUS adj. belonging to the Polemoniaceae, the phlox family.
TROPHONEUROSEStrophoneuroses n. Plural of trophoneurosis.
TROPHONEUROSIS n. a state of deranged nutrition owing to disorder of the trophic action of the nerves.
CHENOPODIACEOUSchenopodiaceous adj. (Botany) Of or relating to the family Chenopodiaceae (goosefoots) (now subfamily Chenopodioideae).
CHENOPODIACEOUS adj. belonging to the goosefoot family.
CONTEMPORANEOUScontemporaneous adj. Existing or created in the same period of time.
CONTEMPORANEOUS adj. existing, occurring, or originating during the same time, also COTEMPORANEOUS.
POISONOUSNESSESPOISONOUSNESS n. POISONOUS, having the quality or effect of poison.
PSEUDOCOELOMATEpseudocoelomate adj. Of, pertaining to, or possessing a pseudocoel.
pseudocoelomate n. Such an animal.
PSEUDOCOELOMATE n. an invertebrate (as a nematode or rotifer) having a body cavity that is a pseudocoel.

Scrabble words — in black are valid world wide — in RED are not valid in North America — in GREEN are valid only in North America.
Definitions are short excerpt from the WikWik.org and 1Word.ws.

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