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There are 16 words containing 2E, L, 2S, X and Y

EXPRESSLYexpressly adv. In an express or explicit manner.
expressly adv. Exclusively.
EXPRESS adv. explicit, clearly stated.
SEXLESSLYsexlessly adv. In a sexless manner, or in a way that lacks sex appeal.
SEXLESS adv. lacking sexual characteristics.
HEXASTYLEShexastyles n. Plural of hexastyle.
HEXASTYLE n. a portico having six columns in front.
OXYGENLESSoxygenless adj. Lacking oxygen.
oxygenless adj. (Of mountain climbing) not assisted with oxygen.
OXYGENLESS adj. without oxygen.
EXCESSIVELYexcessively adv. To an excessive degree.
excessively adv. In excess.
EXCESSIVE adv. beyond what is usual or right; immoderate.
EXPRESSIVELYexpressively adv. In an expressive manner.
EXPRESSIVE adv. full of expression.
EXTRASYSTOLEextrasystole n. (Medicine) A premature contraction of the heart, producing an interruption or irregularity in heartbeat…
EXTRASYSTOLE n. a premature beat of one of the chambers of the heart that leads to momentary arrhythmia.
EXHAUSTLESSLYexhaustlessly adv. Without running out or coming to an end.
EXHAUSTLESS adv. inexhaustible.
EXTRASYSTOLESextrasystoles n. Plural of extrasystole.
EXTRASYSTOLE n. a premature beat of one of the chambers of the heart that leads to momentary arrhythmia.
INEXPRESSIBLYinexpressibly adv. In an inexpressible manner.
INEXPRESSIBLE adv. that cannot be expressed.
SCEUOPHYLAXESSCEUOPHYLAX n. a sacristan.
SEXAGESIMALLYsexagesimally adv. In the sexagesimal system.
SEXAGESIMAL adv. relating to, or based on, sixty.
DECARBOXYLASESdecarboxylases n. Plural of decarboxylase.
DECARBOXYLASE n. any of a group of enzymes that accelerate decarboxylation esp. of amino acids.
INEXPRESSIVELYinexpressively adv. Without expression.
INEXPRESSIVE adv. lacking expression or meaning.
SUPERSEXUALITYsupersexuality n. The quality of being supersexual.
SUPERSEXUALITY n. exceptional sexuality.
CYCLOOXYGENASEScyclooxygenases n. Plural of cyclooxygenase.
cyclo-oxygenases n. Plural of cyclo-oxygenase; Alternative form of cyclooxygenases.

Scrabble words — in black are valid world wide — in RED are not valid in North America — in GREEN are valid only in North America.
Definitions are short excerpt from the WikWik.org and 1Word.ws.

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See this list for:

  • English Wiktionary: 224 words
  • Scrabble in French: 8 words
  • Scrabble in Spanish: 7 words
  • Scrabble in Italian: no word
  • Scrabble in German: no word
  • Scrabble in Romanian: no word


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