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There are 18 words containing 2E, L, 2R, S and X

DEXTRORSELYdextrorsely adv. In a dextrorse manner.
DEXTRORSE adv. rising spirally and turning to the left, also DEXTRORSAL.
EXPLORERSexplorers n. Plural of explorer.
Explorers n. Plural of Explorer.
EXPLORER n. one who explores.
EXTRAVERSIVELYEXTRAVERSIVE adv. turning outwards.
EXTROVERSIVELYextroversively adv. In an extroversive manner.
EXTROVERSIVE adv. characterised by extroversion.
HEXYLRESORCINOLhexylresorcinol n. (Organic chemistry) A hexyl derivative of resorcinol that has anaesthetic, antiseptic and antihelmintic properties.
HEXYLRESORCINOL n. a crystalline phenol used as an antiseptic and anthelmintic.
INTERLOCUTRIXESINTERLOCUTRIX n. a female interlocutor, also INTERLOCUTRESS, INTERLOCUTRICE.
IRREFLEXIONSIRREFLEXION n. not being reflective, also IRREFLECTION.
LEXICOGRAPHERSlexicographers n. Plural of lexicographer.
LEXICOGRAPHER n. an author or editor of a dictionary.
PERPLEXERSperplexers n. Plural of perplexer.
PERPLEXER n. one who perplexes.
PREMAXILLARIESpremaxillaries n. Plural of premaxillary.
PREMAXILLARY n. the premaxilla, a bone in front of the maxilla, also PREMAXILLA.
REEXPLORATIONSreexplorations n. Plural of reexploration.
REEXPLORESreexplores v. Third-person singular simple present indicative form of reexplore.
REEXPLORE v. to explore again.
RELAXERSrelaxers n. Plural of relaxer.
RELAXER n. one that relaxes.
RETROFLEXESretroflexes n. Plural of retroflex.
RETROFLEX v. to bend back.
RETROFLEXIONSretroflexions n. Plural of retroflexion.
RETROFLEXION n. the state of being bent back, also RETROFLECTION.
RETROSEXUALretrosexual n. A man who embraces traditional masculinity in his dress and behavior.
retrosexual n. (Humorous) One who has not had sex in a very long time.
RETROSEXUAL n. a man with traditional sexual attitudes.
RETROSEXUALSretrosexuals n. Plural of retrosexual.
RETROSEXUAL n. a man with traditional sexual attitudes.
SUPERLUXURIESsuperluxuries n. Plural of superluxury.
SUPERLUXURY n. extreme luxury.

Scrabble words — in black are valid world wide — in RED are not valid in North America — in GREEN are valid only in North America.
Definitions are short excerpt from the WikWik.org and 1Word.ws.

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