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There are 20 words containing 2E, H, M, 2S and Z

EMPHASIZESemphasizes v. Third-person singular simple present indicative form of emphasize.
EMPHASIZE v. to add emphasis to, also EMPHASISE.
HYSTERECTOMIZEShysterectomizes v. Third-person singular simple present indicative form of hysterectomize.
HYSTERECTOMIZE v. to remove the womb, also HYSTERECTOMISE.
METAPHYSICIZESMETAPHYSICIZE v. to make metaphysical, also METAPHYSICISE.
METATHESIZESmetathesizes v. Third-person singular simple present indicative form of metathesize.
METATHESIZE v. to transpose by metathesis, also METATHESISE.
MISEMPHASIZEmisemphasize v. To emphasize incorrectly or inappropriately.
MISEMPHASIZE v. to emphasize wrongly, also MISEMPHASISE.
MISEMPHASIZEDmisemphasized v. Simple past tense and past participle of misemphasize.
MISEMPHASIZE v. to emphasize wrongly, also MISEMPHASISE.
MISEMPHASIZESmisemphasizes v. Third-person singular simple present indicative form of misemphasize.
MISEMPHASIZE v. to emphasize wrongly, also MISEMPHASISE.
OVEREMPHASIZESoveremphasizes v. Third-person singular simple present indicative form of overemphasize.
OVEREMPHASIZE v. to emphasise to excess, also OVEREMPHASISE.
REEMPHASIZESreemphasizes v. Third-person singular simple present indicative form of reemphasize.
REEMPHASIZE v. to emphasise again, also REEMPHASISE.
SCHEMATIZESschematizes v. Third-person singular simple present indicative form of schematize.
SCHEMATIZE v. to make a scheme of, also SCHEMATISE.
SCHEMOZZLESschemozzles n. Plural of schemozzle.
schemozzles v. Third-person singular simple present indicative form of schemozzle.
SCHEMOZZLE v. (Yiddish) to make off, also SHEMOZZLE, SHIMOZZLE, SHLEMOZZLE.
SCHIZOMYCETESSchizomycetes prop.n. (Archaic) A taxonomic class within the kingdom Plantae – all or some bacteria, in any of several phyla.
SCHIZOMYCETE n. any microscopic organism of the class Schizomycetes.
SCHMELZESSchmelzes prop.n. Plural of Schmelz.
SCHMELZ n. (German) a kind of glass of a red or ruby color, made in Bohemia, also SCHMELZE.
SHEMOZZLESshemozzles n. Plural of shemozzle.
SHEMOZZLE v. to make off, also SCHEMOZZLE, SHIMOZZLE, SHLEMOZZLE.
SHLEMOZZLESshlemozzles n. Plural of shlemozzle.
SHLEMOZZLE v. (Yiddish) to make off, also SCHEMOZZLE, SHEMOZZLE, SHIMOZZLE.
SULFAMETHAZINESSULFAMETHAZINE n. an American name for sulfadimidine, a white odourless crystalline compound formerly used in medicine in the treatment of bacterial infections.
SUPERHUMANIZESsuperhumanizes v. Third-person singular simple present indicative form of superhumanize.
SUPERHUMANIZE v. to make superhuman, also SUPERHUMANISE.
UNDEREMPHASIZESunderemphasizes v. Third-person singular simple present indicative form of underemphasize.
UNDEREMPHASIZE v. to emphasise insufficiently, also UNDEREMPHASISE.
WELTSCHMERZESWELTSCHMERZ n. (German) mental depression or apathy caused by comparison of the actual state of the world with an ideal state.
ZOOCHEMISTRIESZOOCHEMISTRY n. the chemistry of the animal body.

Scrabble words — in black are valid world wide — in RED are not valid in North America — in GREEN are valid only in North America.
Definitions are short excerpt from the 1Word.ws and WikWik.org.

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