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There are 5 words containing 2E, H, L, 2T and X

SIXTEENTHLYsixteenthly adv. In the sixteenth place; sixteenth in a row.
SIXTEENTH adv. number sixteen in sequence.
HYPERTEXTUALhypertextual adj. Of or relating to hypertext.
METHYLXANTHINEmethylxanthine n. (Organic chemistry) Any of a group of compounds, such as caffeine, formed through the methylation of xanthines.
METHYLXANTHINE n. a methylated xanthine derivative, such as caffeine, theobromine, or theophylline.
HETEROSEXUALITYheterosexuality n. The state of being sexually and romantically attracted primarily or exclusively to persons of the opposite sex.
heterosexuality n. Sexual activity with a person of the opposite sex.
HETEROSEXUALITY n. the state of being heterosexual.
METHYLXANTHINESmethylxanthines n. Plural of methylxanthine.
METHYLXANTHINE n. a methylated xanthine derivative, such as caffeine, theobromine, or theophylline.

Scrabble words — in black are valid world wide — in RED are not valid in North America — in GREEN are valid only in North America.
Definitions are short excerpt from the WikWik.org and 1Word.ws.

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