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There are 12 words containing 2E, F, N, S, U and Z

CENTRIFUGALIZEScentrifugalizes v. Third-person singular simple present indicative form of centrifugalize.
CENTRIFUGALIZE v. to subject to centrifugal force, also CENTRIFUGALISE.
FLUPHENAZINESfluphenazines n. Plural of fluphenazine.
FLUPHENAZINE n. a tranquilizer used esp. in the form of its hydrochloride.
FROUZINESSESFROUZINESS n. the state of being frouzy, fusty, stuffy.
FUZZINESSESfuzzinesses n. Plural of fuzziness.
FUZZINESS n. the state of being fuzzy.
SUBFREEZINGsubfreezing adj. Colder than the freezing point of water; below 0 degrees C or 32 degrees F.
SUBFREEZING adj. below freezing.
SULFAMETHAZINEsulfamethazine n. Sulfadimidine.
SULFAMETHAZINE n. an American name for sulfadimidine, a white odourless crystalline compound formerly used in medicine in the treatment of bacterial infections.
SULFAMETHAZINESSULFAMETHAZINE n. an American name for sulfadimidine, a white odourless crystalline compound formerly used in medicine in the treatment of bacterial infections.
UNFEUDALIZESunfeudalizes v. Third-person singular simple present indicative form of unfeudalize.
UNFEUDALIZE v. to deprive of a feudal character, also UNFEUDALISE.
UNFREEZESunfreezes v. Third-person singular simple present indicative form of unfreeze.
UNFREEZE v. to cause to thaw.
UNFREEZINGSUNFREEZING n. a thawing, a release of assets.
ZESTFULNESSzestfulness n. State or condition of being zestful or enthusiastic.
ZESTFULNESS n. the state of being zestful.
ZESTFULNESSESzestfulnesses n. Plural of zestfulness.
ZESTFULNESS n. the state of being zestful.

Scrabble words — in black are valid world wide — in RED are not valid in North America — in GREEN are valid only in North America.
Definitions are short excerpt from the 1Word.ws and WikWik.org.

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