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There are 8 words containing 2E, F, N, S, U and X

EXTRAFORANEOUSextraforaneous adj. (Nonce word, archaic) outdoor.
EXTRAFORANEOUS adj. outdoors.
FLUOXETINESFLUOXETINE n. an antidepressant drug that increases the levels of serotonin in the central nervous system.
FUNPLEXESFUNPLEX n. a building with facilities for sports and games.
GENUFLEXIONSgenuflexions n. Plural of genuflexion.
GENUFLEXION n. the bending of the knees in respect or worship, also GENUFLECTION.
INFLEXURESinflexures n. Plural of inflexure.
INFLEXURE n. an inflection; a bend or fold.
METHOXYFLURANESmethoxyfluranes n. Plural of methoxyflurane.
METHOXYFLURANE n. a potent general anaesthetic administered as a vapor.
UNFIXEDNESSunfixedness n. The property of being unfixed.
UNFIXEDNESS n. the state of not being fixed.
UNFIXEDNESSESUNFIXEDNESS n. the state of not being fixed.

Scrabble words — in black are valid world wide — in RED are not valid in North America — in GREEN are valid only in North America.
Definitions are short excerpt from the 1Word.ws and WikWik.org.

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