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There are 10 words containing 2E, F, L, 2S and Z

DESULFURIZERSDESULFURIZER n. something for removing sulfur, also DESULFURISER.
DESULFURIZESdesulfurizes v. Third-person singular simple present indicative form of desulfurize.
DESULFURIZE v. to remove the sulphur from a compound, also DESULFURISE, DESULPHURISE, DESULPHURIZE.
FIZZENLESSfizzenless adj. (Scotland) Lacking force or energy; lethargic.
FIZZENLESS adj. (Scots) weak, feeble, also FOISONLESS, FUSHIONLESS, FUSIONLESS.
FRIZZLINESSESFRIZZLINESS n. the state of being frizzly.
FUZELESSFUZELESS adj. without a fuze, also FUSELESS.
PROFESSIONALIZEprofessionalize v. To make something professional.
professionalize v. To advance an occupation to the level of a profession.
PROFESSIONALIZE v. to give a professional character to, also PROFESSIONALISE.
SULFAMETHAZINESSULFAMETHAZINE n. an American name for sulfadimidine, a white odourless crystalline compound formerly used in medicine in the treatment of bacterial infections.
SUPERFICIALIZESsuperficializes v. Third-person singular simple present indicative form of superficialize.
SUPERFICIALIZE v. to make superficial, also SUPERFICIALISE.
ZESTFULNESSzestfulness n. State or condition of being zestful or enthusiastic.
ZESTFULNESS n. the state of being zestful.
ZESTFULNESSESzestfulnesses n. Plural of zestfulness.
ZESTFULNESS n. the state of being zestful.

Scrabble words — in black are valid world wide — in RED are not valid in North America — in GREEN are valid only in North America.
Definitions are short excerpt from the 1Word.ws and WikWik.org.

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