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There are 4 words containing 2E, F, L, M, S and Z

DEFORMALIZESdeformalizes v. Third-person singular simple present indicative form of deformalize.
DEFORMALIZE v. to make less formal, also DEFORMALISE.
DEFAMILIARIZESdefamiliarizes v. Third-person singular simple present indicative form of defamiliarize.
SULFAMETHAZINEsulfamethazine n. Sulfadimidine.
SULFAMETHAZINE n. an American name for sulfadimidine, a white odourless crystalline compound formerly used in medicine in the treatment of bacterial infections.
SULFAMETHAZINESSULFAMETHAZINE n. an American name for sulfadimidine, a white odourless crystalline compound formerly used in medicine in the treatment of bacterial infections.

Scrabble words — in black are valid world wide — in RED are not valid in North America — in GREEN are valid only in North America.
Definitions are short excerpt from the WikWik.org and 1Word.ws.

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