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There are 3 words containing 3E, F, 2R and X

IRREFLEXIVEirreflexive adj. (Set theory) Of a binary relation R on X: such that no element of X is R-related to itself.
IRREFLEXIVE adj. not reflecting.
RETROFLEXEDretroflexed adj. Bent in a posterior (backwards) direction, as the uterus.
retroflexed adj. (Phonetics) Being retroflex.
RETROFLEX v. to bend back.
RETROFLEXESretroflexes n. Plural of retroflex.
RETROFLEX v. to bend back.

Scrabble words — in black are valid world wide — in RED are not valid in North America — in GREEN are valid only in North America.
Definitions are short excerpt from the WikWik.org and 1Word.ws.

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