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There are 3 eight-letter words containing E, I, L, N, O, P and U

NEUROPILneuropil n. A fibrous network of nervous tissue that forms the gray matter of the brain.
NEUROPIL n. a network of axons, dendrites and synapses within the central nervous system.
POULAINEpoulaine n. A long, pointed toe of a shoe, a style fashionable in the 14th and 15th centuries.
poulaine n. A shoe in such a style.
poulaine n. Rare form of poleyn (“knee armor”).
UNPOLITEunpolite adj. (Obsolete) Unsophisticated, not refined; coarse, uncultured.
unpolite adj. (Now chiefly North America) Lacking in good manners; impolite, discourteous.
UNPOLITE adj. not polite.

Scrabble words — in black are valid world wide — in RED are not valid in North America — in GREEN are valid only in North America.
Definitions are short excerpt from the WikWik.org and 1Word.ws.

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