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There are 19 eight-letter words containing 2E, I, N, 2S and T

CENTESIScentesis n. (Medicine, surgery) puncture or perforation.
-centesis suff. (Medicine) Puncture and aspiration of.
CENTESIS n. (Greek) a surgical puncture.
DESTINESdestines v. Third-person singular simple present indicative form of destine.
DESTINE v. to determine beforehand.
EENSIESTEENSY adj. (colloquial) very small.
ENSUITESensuites n. Plural of ensuite.
en-suites n. Plural of en-suite.
en␣suites n. Plural of en suite.
ESSONITEessonite n. (Mineralogy) Cinnamon stone, a variety of garnet.
ESSONITE n. cinnamon stone, a variety of garnet, also HESSONITE.
ETESIANSetesians n. Plural of etesian.
ETESIAN n. a NW wind that recurs annually in the summer in the eastern part of the Mediterranean Sea.
INTERESSinteress v. (Transitive, obsolete) interest.
INTERESS v. (obsolete) to interest, also INTERESSE.
LITENESSLITENESS n. the state of being lite.
NEWSIESTnewsiest adj. Superlative form of newsy: most newsy.
NEWSY adj. full of news.
PENTISESpentises n. Plural of pentise.
PENTISE v. to provide with a penthouse, also PENTICE.
SENTRIESsentries n. Plural of sentry.
SENTRY n. the one who stands guard.
SESTINESsestines n. Plural of sestine.
SESTINE n. an old verse-form of six six-lined stanzas, also SESTINA, SEXTAIN.
SETLINESsetlines n. Plural of setline.
SETLINE n. a strong fishing line between buoys.
SIENITESsienites n. Plural of sienite.
SIENITE n. a coarse-grained igneous rock, allied to granite, also SYENITE.
SIXTEENSsixteens n. Plural of sixteen.
SIXTEEN n. a number.
SYENITESsyenites n. Plural of syenite.
SYENITE n. a coarse-grained igneous rock, allied to granite, also SIENITE.
TENIASESteniases n. Plural of teniasis.
TENIASIS n. an infestation with tapeworms.
TENNISEStennises n. Plural of tennis.
tennises v. Third-person singular simple present indicative form of tennis.
TENNIS n. an outdoor ball game.
TRENISESTRENISE n. (French) the fourth movement of a quadrille.

Scrabble words — in black are valid world wide — in RED are not valid in North America — in GREEN are valid only in North America.
Definitions are short excerpt from the WikWik.org and 1Word.ws.

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