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There are 2 eight-letter words containing 2E, I, L, 2P and S

EPILEPSYepilepsy n. (Pathology) A medical condition in which the sufferer experiences seizures (or convulsions) and blackouts.
EPILEPSY n. a disorder of the nervous system.
PIPELESSpipeless adj. Without pipes.
PIPELESS adj. without a pipe.

Scrabble words — in black are valid world wide — in RED are not valid in North America — in GREEN are valid only in North America.
Definitions are short excerpt from the WikWik.org and 1Word.ws.

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