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There are 8 eight-letter words containing 2E, I, L, M, N and S

ERMELINSermelins n. Plural of ermelin.
ERMELIN n. (archaic) ermine.
HEMLINEShemlines n. Plural of hemline.
HEMLINE n. the bottom edge of a garment.
ISLESMENislesmen n. Plural of islesman.
ISLESMAN n. an islander, also ISLEMAN.
LINESMENlinesmen n. Plural of linesman.
LINESMAN n. an official who helps the referee or umpire in various sports, esp. by indicating when the ball has gone out of play.
MELANISEmelanise v. Alternative form of melanize.
MELANISE v. to make dark, also MELANIZE.
MYELINESmyelines n. Plural of myeline.
MYELINE n. the fatty substance forming the medullary sheath of nerve-fibres, also MYELIN.
SELENIUMselenium n. A nonmetallic chemical element (symbol Se) with an atomic number of 34, used mainly in glassmaking and…
selenium n. A single atom of this element.
SELENIUM n. a nonmetallic solid element used in photoelectric cells.
SEMILUNEsemilune n. (Geometry) The half of a lune.
SEMILUNE n. (French) a half-moon fortification, a ravelin, also DEMILUNE.

Scrabble words — in black are valid world wide — in RED are not valid in North America — in GREEN are valid only in North America.
Definitions are short excerpt from the WikWik.org and 1Word.ws.

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