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There are 4 eight-letter words containing 2E, 2I, M, R and S

DIMERISEdimerise v. Alternative spelling of dimerize.
DIMERISE v. to make into a dimer, also DIMERIZE.
ITEMISERitemiser n. Alternative form of itemizer.
ITEMISER n. one that itemizes, also ITEMIZER.
MISERIESmiseries n. Plural of misery.
MISERY n. a state of great suffering.
RIEMPIESriempies n. Plural of riempie.
RIEMPIE n. (South African) a long riem about the width of a shoelace, used as string.

Scrabble words — in black are valid world wide — in RED are not valid in North America — in GREEN are valid only in North America.
Definitions are short excerpt from the WikWik.org and 1Word.ws.

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