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There are 4 twelve-letter words containing E, 3M, P, R and S

HEMIMORPHISMhemimorphism n. The condition of being hemimorphic.
HEMIMORPHISM n. the state of being hemimorphic.
MENISPERMUMSMENISPERMUM n. any plant of the moonseed genus Menispermum.
MESOMORPHISMmesomorphism n. The condition of being mesomorphic.
MESOMORPHISM n. the state of being mesomorphic.
METAMORPHISMmetamorphism n. (Geology) The process by which rocks are changed into other forms by the application of heat and/or pressure.
metamorphism n. (Zoology) The process by which insects develop through life stages, for example, those of embryo, larva…
metamorphism n. (By extension) Any dramatic change from one thing to another.

Scrabble words — in black are valid world wide — in RED are not valid in North America — in GREEN are valid only in North America.
Definitions are short excerpt from the WikWik.org and 1Word.ws.

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