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There are 6 twelve-letter words containing E, I, M, S, T, U and X

AMBIDEXTROUSambidextrous adj. Having equal ability in both hands; in particular, able to write equally well with both hands.
ambidextrous adj. Equally usable by left-handed and right-handed people (as a tool or instrument).
ambidextrous adj. (Archaic) Practising or siding with both parties.
AUTOTOXEMIASautotoxemias n. Plural of autotoxemia.
AUTOTOXEMIA n. self-poisoning caused by absorption of toxic products originating within the body, also AUTOTOXAEMIA.
EXTRAMUSICALextramusical adj. Apart from and in addition to music.
EXTRAMUSICAL adj. lying outside the province of music.
MULTIPLEXERSmultiplexers n. Plural of multiplexer.
MULTIPLEXER n. a device enabling a computer to transmit data to many terminals by switching quickly from one user's data to another, also MULTIPLEXOR.
MULTIPLEXORSmultiplexors n. Plural of multiplexor.
MULTIPLEXOR n. a device enabling a computer to transmit data to many terminals by switching quickly from one user's data to another, also MULTIPLEXER.
XIPHISTERNUMxiphisternum n. (Biology, medicine) Synonym of xiphoid process.
XIPHISTERNUM n. the posterior and smallest of the three divisions of the sternum.

Scrabble words — in black are valid world wide — in RED are not valid in North America — in GREEN are valid only in North America.
Definitions are short excerpt from the WikWik.org and 1Word.ws.

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