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There are 8 twelve-letter words containing E, 2I, 2O, R and X

DORSIFLEXIONdorsiflexion n. (Medicine) Flexion in the dorsal direction.
DORSIFLEXION n. a bending backwards; a bending of the back.
EXCORIATIONSexcoriations n. Plural of excoriation.
EXCORIATION n. the act of excoriating.
EXPOSITORILYexpositorily adv. In an expository fashion.
EXPOSITORY adv. pertaining to, or containing, exposition.
EXPROMISSIONexpromission n. (Law) The intervention of a new debtor, substituted for the former one, who is consequently discharged…
EXPROMISSION n. relieving another person's debt by taking it upon oneself.
EXTORTIONISTextortionist n. Someone who extorts; an extortioner.
EXTORTIONIST n. one who practises extortion.
PEROXIDATIONperoxidation n. (Chemistry) Any oxidation reaction, especially of an oxide, that produces a peroxide.
peroxidation n. (Organic chemistry) The reaction of a double bond with a peroxide.
PEROXIDATION n. the creation of a peroxide.
REOXIDATIONSreoxidations n. Plural of reoxidation.
REOXIDATION n. the process of reoxidizing.
THIXOTROPIESTHIXOTROPY n. the property of certain gels of becoming fluid when agitated and of reverting back to a gel when left to stand.

Scrabble words — in black are valid world wide — in RED are not valid in North America — in GREEN are valid only in North America.
Definitions are short excerpt from the WikWik.org and 1Word.ws.

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