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There are 19 twelve-letter words containing E, H, L, R, S and 2U

DESULPHURATEdesulphurate v. (Transitive) To deprive of sulphur.
DESULPHURATE v. to remove sulphur from.
DESULPHURINGdesulphuring v. Present participle of desulphur.
DESULPHUR v. to remove sulphur from, also DESULFUR.
DESULPHURISEdesulphurise v. (British spelling) Alternative spelling of desulfurize (American spelling).
DESULPHURISE v. to remove the sulphur from a compound, also DESULFURISE, DESULFURIZE, DESULPHURIZE.
DESULPHURIZEdesulphurize v. (Oxford) Alternative spelling of desulfurize (American spelling).
DESULPHURIZE v. to remove the sulphur from a compound, also DESULFURISE, DESULFURIZE, DESULPHURISE.
DISULPHURETSdisulphurets n. Plural of disulphuret.
DISULPHURET n. (obsolete) a sulphide containing two atoms of sulphur to the molecule, also DISULFID, DISULFIDE, DISULPHIDE.
DOLICHURUSESDOLICHURUS n. (Greek) a dactylic hexameter with a redundant syllable at the end.
HUMOURLESSLYhumourlessly adv. Alternative spelling of humorlessly.
HUMOURLESS adv. without humour, also HUMORLESS.
OCHROLEUCOUSochroleucous adj. Yellowish-white; having a faint tint of dingy yellow.
OCHROLEUCOUS adj. yellowish white.
PERSULPHURICPERSULPHURIC adj. denoting a type of acid, also PERSULFURIC.
PULCHRITUDESpulchritudes n. Plural of pulchritude.
PULCHRITUDE n. beauty.
SLAUGHTEROUSslaughterous adj. Prone to slaughtering.
SLAUGHTEROUS adj. of or relating to slaughter.
SULPHURETINGsulphureting v. Present participle of sulphuret.
SULPHURET v. to treat with sulfur, also SULFURET.
SULPHURETTEDsulphuretted adj. Alternative spelling of sulfuretted.
SULPHURET v. to treat with sulfur, also SULFURET.
SUPERHUMANLYsuperhumanly adv. In a superhuman way, or to a superhuman extent.
SUPERHUMAN adv. being above the human.
SUPERHUMERALsuperhumeral n. An imperial decorative collar worn in Byzantium.
superhumeral n. Anything worn upon the shoulders, such as the amice, the pallium, or the ephod.
SUPERHUMERAL n. an ecclesiastical garment worn over the shoulders.
SUPERSLEUTHSsupersleuths n. Plural of supersleuth.
SUPERSLEUTH n. a very effective detective.
THUNDEROUSLYthunderously adv. In a thunderous manner, very loudly.
THUNDEROUS adv. sounding like thunder, also THUNDROUS.
TRUTHFULNESStruthfulness n. The quality of being truthful.
TRUTHFULNESS n. the state of being truthful.
UNSEPULCHREDunsepulchred adj. Not laid in a sepulchre.
UNSEPULCHRED adj. not sepulchred.

Scrabble words — in black are valid world wide — in RED are not valid in North America — in GREEN are valid only in North America.
Definitions are short excerpt from the 1Word.ws and WikWik.org.

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