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There are 6 twelve-letter words containing 2E, 2M, 2O and P

EMPOISONMENTempoisonment n. The act of poisoning.
EMPOISONMENT n. the act of poisoning.
MESOMORPHIESMESOMORPHY n. the state of being a mesomorph.
METAMORPHOSEmetamorphose v. (Of a moth or insect, intransitive) To undergo metamorphosis.
metamorphose v. (By extension, intransitive) To undergo some transformation.
metamorphose v. (Transitive) To transform (something) so that it has a completely different appearance.
PAMPELMOOSESpampelmooses n. Plural of pampelmoose.
PAMPELMOOSE n. (Dutch) the shaddock or grapefruit, also PAMPELMOUSE, POMELO, POMPELMOOSE, POMPELMOUS, POMPELMOUSE, POMPELO, PUMELO, PUMMELO.
POMPELMOOSESpompelmooses n. Plural of pompelmoose.
POMPELMOOSE n. (Dutch) the shaddock or grapefruit, also PAMPELMOOSE, PAMPELMOUSE, POMELO, POMPELMOUS, POMPELMOUSE, POMPELO, PUMELO, PUMMELO.
POMPELMOUSESpompelmouses n. Plural of pompelmous.
pompelmouses n. Plural of pompelmouse.
POMPELMOUSE n. (Dutch) the shaddock or grapefruit, also PAMPELMOOSE, PAMPELMOUSE, POMELO, POMPELMOOSE, POMPELMOUS, POMPELO, PUMELO, PUMMELO.

Scrabble words — in black are valid world wide — in RED are not valid in North America — in GREEN are valid only in North America.
Definitions are short excerpt from the WikWik.org and 1Word.ws.

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