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There are 4 twelve-letter words containing 2E, L, 2R, T and X

EXTRANUCLEARextranuclear adj. Outside the nucleus.
extranuclear adj. (Biology) Outside the nucleus but within the cell cytoplasm.
EXTRANUCLEAR adj. situated in or affecting the parts of a cell external to the nucleus.
RETROFLEXINGRETROFLEX v. to bend back.
RETROFLEXIONretroflexion n. The act of retroflexing; the state of being retroflexed.
RETROFLEXION n. the state of being bent back, also RETROFLECTION.
RETROSEXUALSretrosexuals n. Plural of retrosexual.
RETROSEXUAL n. a man with traditional sexual attitudes.

Scrabble words — in black are valid world wide — in RED are not valid in North America — in GREEN are valid only in North America.
Definitions are short excerpt from the WikWik.org and 1Word.ws.

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