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There are 14 twelve-letter words containing 2E, H, R, S and 2U

DESULPHURATEdesulphurate v. (Transitive) To deprive of sulphur.
DESULPHURATE v. to remove sulphur from.
DESULPHURISEdesulphurise v. (British spelling) Alternative spelling of desulfurize (American spelling).
DESULPHURISE v. to remove the sulphur from a compound, also DESULFURISE, DESULFURIZE, DESULPHURIZE.
DESULPHURIZEdesulphurize v. (Oxford) Alternative spelling of desulfurize (American spelling).
DESULPHURIZE v. to remove the sulphur from a compound, also DESULFURISE, DESULFURIZE, DESULPHURISE.
EURYTHERMOUSeurythermous adj. Synonym of eurythermal.
EURYTHERMOUS adj. tolerating a wide range of temperature, also EURYTHERMAL, EURYTHERMIC.
HARQUEBUSIERharquebusier n. Alternative form of arquebusier.
HARQUEBUSIER n. a soldier armed with an arquebus.
HARQUEBUSSESharquebusses n. Plural of harquebus.
harquebusses n. Plural of harquebuss.
HARQUEBUSS n. an early type of portable firearm; spec. one supported on a tripod by a hook or on a forked rest, also ARQUEBUS, HARQUEBUS, HARQUEBUSE.
HUMBUGGERIEShumbuggeries n. Plural of humbuggery.
HUMBUGGERY n. deception.
SULPHURETTEDsulphuretted adj. Alternative spelling of sulfuretted.
SULPHURET v. to treat with sulfur, also SULFURET.
SUMMERHOUSESsummerhouses n. Plural of summerhouse.
summer-houses n. Plural of summer-house.
summer␣houses n. Plural of summer house.
SUPERHUMERALsuperhumeral n. An imperial decorative collar worn in Byzantium.
superhumeral n. Anything worn upon the shoulders, such as the amice, the pallium, or the ephod.
SUPERHUMERAL n. an ecclesiastical garment worn over the shoulders.
SUPERSLEUTHSsupersleuths n. Plural of supersleuth.
SUPERSLEUTH n. a very effective detective.
UNDERBRUSHEDunderbrushed v. Simple past tense and past participle of underbrush.
UNDERBRUSH v. to clear of underbrush.
UNDERBRUSHESunderbrushes n. Plural of underbrush.
UNDERBRUSH n. shrubs, small trees, and the like, in a wood or forest, growing beneath large trees.
UNSEPULCHREDunsepulchred adj. Not laid in a sepulchre.
UNSEPULCHRED adj. not sepulchred.

Scrabble words — in black are valid world wide — in RED are not valid in North America — in GREEN are valid only in North America.
Definitions are short excerpt from the WikWik.org and 1Word.ws.

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